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Esam endothelial cell-specific adhesion molecule [ Mus musculus (house mouse) ]

Gene ID: 69524, updated on 31-Jan-2019

Summary

Official Symbol
Esamprovided by MGI
Official Full Name
endothelial cell-specific adhesion moleculeprovided by MGI
Primary source
MGI:MGI:1916774
See related
Ensembl:ENSMUSG00000001946
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Esam1; W117m; 2310008D05Rik
Expression
Broad expression in lung adult (RPKM 97.8), subcutaneous fat pad adult (RPKM 50.9) and 22 other tissues See more
Orthologs

Genomic context

See Esam in Genome Data Viewer
Location:
9; 9 A4
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (37528089..37538319)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (37335674..37345904)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene roundabout guidance receptor 3 Neighboring gene Myb/SANT-like DNA-binding domain containing 2 Neighboring gene V-set and immunoglobulin domain containing 2 Neighboring gene neurogranin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
bicellular tight junction IDA
Inferred from Direct Assay
more info
PubMed 
cell junction IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
endothelial cell-selective adhesion molecule

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027102.3NP_081378.1  endothelial cell-selective adhesion molecule precursor

    See identical proteins and their annotated locations for NP_081378.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript.
    Source sequence(s)
    AI414314, AK009223, BG077536, BQ043033, BY119695, CJ048383
    Consensus CDS
    CCDS22979.1
    UniProtKB/Swiss-Prot
    Q925F2
    UniProtKB/TrEMBL
    Q3U102
    Related
    ENSMUSP00000002011.7, ENSMUST00000002011.13
    Conserved Domains (3) summary
    smart00408
    Location:170234
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:169244
    IG_like; Immunoglobulin like
    pfam07686
    Location:42153
    V-set; Immunoglobulin V-set domain

RNA

  1. NR_136939.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC105958, AI414314

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    37528089..37538319
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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