U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SCML2 Scm polycomb group protein like 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694404, updated on 10-Feb-2026
Official Symbol
SCML2provided by VGNC
Official Full Name
Scm polycomb group protein like 2provided by VGNC
Primary source
VGNC:VGNC:76979
Locus tag
EGK_20307
See related
Ensembl:ENSMMUG00000005084
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See SCML2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) X NC_133426.1 (17979368..18096811, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) X NC_041774.1 (17998617..18116738, complement)

Chromosome X - NC_133426.1Genomic Context describing neighboring genes Neighboring gene retinoic acid induced 2 Neighboring gene BEN domain containing 2 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene cyclin dependent kinase like 5 Neighboring gene retinoschisin 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
sex comb on midleg-like protein 2
Names
Sex comb on midleg-like protein 2
sex comb on midleg like 2

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261359.1 → NP_001248288.1  sex comb on midleg-like protein 2

    See identical proteins and their annotated locations for NP_001248288.1

    Status: PROVISIONAL

    Source sequence(s)
    JU473969
    UniProtKB/TrEMBL
    A0A663D791, A0A8J8YMI1, F7C3Y4, G7NSC2
    Related
    ENSMMUP00000006741.3, ENSMMUT00000007173.4
    Conserved Domains (4) summary
    cd09578
    Location:626 → 697
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:142 → 240
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam12140
    Location:356 → 465
    SLED; SLED domain
    pfam17208
    Location:277 → 324
    RBR; RNA binding Region

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133426.1 Reference T2T-MMU8v2.0

    Range
    17979368..18096811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077987449.1 → XP_077843575.1  sex comb on midleg-like protein 2 isoform X2

  2. XM_015126944.3 → XP_014982430.1  sex comb on midleg-like protein 2 isoform X1

    Conserved Domains (2) summary
    smart00561
    Location:142 → 240
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam12140
    Location:356 → 465
    DUF3588; Protein of unknown function (DUF3588)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials