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H2bw2 H2B.W histone 2 [ Mus musculus (house mouse) ]

Gene ID: 69389, updated on 8-Feb-2024


Official Symbol
H2bw2provided by MGI
Official Full Name
H2B.W histone 2provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000048155 AllianceGenome:MGI:1916639
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2bfm; H2bfw; H2bl2; 1700014N06Rik
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family. [provided by RefSeq, Nov 2015]
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Genomic context

X F1; X 59.1 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135828074..135829122)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136927325..136928373)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene RAB9B, member RAS oncogene family Neighboring gene predicted gene 15026 Neighboring gene glycogen synthase kinase 3 alpha pseudogene Neighboring gene thymosin beta 15b2 Neighboring gene thymosin beta 15b like

Genomic regions, transcripts, and products



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information


Clone Names

  • MGC151453, MGC151457

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
enables structural constituent of chromatin ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
part_of nucleosome ISO
Inferred from Sequence Orthology
more info
located_in nucleus ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
histone variant H2bl2
H2B histone family, member M

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027067.2NP_081343.1  histone variant H2bl2

    See identical proteins and their annotated locations for NP_081343.1

    Status: REVIEWED

    Source sequence(s)
    AK005982, BC117076
    Consensus CDS
    ENSMUSP00000055261.4, ENSMUST00000059808.5
    Conserved Domains (1) summary
    H2B; Histone H2B

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000086.8 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)