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IL6R interleukin 6 receptor [ Gallus gallus (chicken) ]

Gene ID: 693252, updated on 5-Sep-2025
Symbol
IL6Rprovided by CGNC
Full Name
interleukin 6 receptorprovided by CGNC
Primary source
CGNC:54349
See related
Ensembl:ENSGALG00010027886
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
IL6RA
Orthologs
human mouse all
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See IL6R in Genome Data Viewer
Location:
chromosome: 25
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 25 NC_052556.1 (1936739..1942224)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 25 NC_052597.1 (2062836..2068350)

Chromosome 25 - NC_052556.1Genomic Context describing neighboring genes Neighboring gene aquaporin 10 Neighboring gene ATPase phospholipid transporting 8B2 Neighboring gene Src homology 2 domain containing E Neighboring gene ubiquitin conjugating enzyme E2 Q1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization and expression analysis of a chicken interleukin-6 receptor alpha. Nishimichi N, et al. Dev Comp Immunol, 2006. PMID 16153708
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. identified chicken cDNA sequence encodes a chicken interleukin-6 homologue
    Title: Characterization and expression analysis of a chicken interleukin-6 receptor alpha.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
interleukin-6 receptor subunit alpha
Names
interleukin 6 receptor alpha

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044675.2 → NP_001038140.1  interleukin-6 receptor subunit alpha precursor

    See identical proteins and their annotated locations for NP_001038140.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000351
    UniProtKB/TrEMBL
    A0A8V1AG75, Q5DWQ5
    Related
    ENSGALP00010041331.1, ENSGALT00010067588.1
    Conserved Domains (2) summary
    smart00060
    Location:209 → 293
    FN3; Fibronectin type 3 domain
    cl21522
    Location:111 → 206
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052556.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1936739..1942224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025143427.3 → XP_024999195.2  interleukin-6 receptor subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8V1ADN3, A0A8V1AG75
    Related
    ENSGALP00010041332.1, ENSGALT00010067589.1
    Conserved Domains (1) summary
    smart00060
    Location:215 → 299
    FN3; Fibronectin type 3 domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052597.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2062836..2068350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046932676.1 → XP_046788632.1  interleukin-6 receptor subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG75
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials