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Izumo3 IZUMO family member 3 [ Mus musculus (house mouse) ]

Gene ID: 69314, updated on 12-May-2024

Summary

Official Symbol
Izumo3provided by MGI
Official Full Name
IZUMO family member 3provided by MGI
Primary source
MGI:MGI:1916564
See related
Ensembl:ENSMUSG00000028533 AllianceGenome:MGI:1916564
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700011H22Rik
Summary
Enables protein homodimerization activity. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to human IZUMO3 (IZUMO family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 9.1) See more
Orthologs
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Genomic context

See Izumo3 in Genome Data Viewer
Location:
4 C5; 4 43.16 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (92032555..92035462, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (92144318..92147225, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene glutaredoxin 3 pseudogene Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 40203 Neighboring gene La ribonucleoprotein 7, transcriptional regulator, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (1)  1 citation

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
izumo sperm-egg fusion protein 3
Names
transmembrane protein C9orf134

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027034.1NP_081310.1  izumo sperm-egg fusion protein 3 precursor

    See identical proteins and their annotated locations for NP_081310.1

    Status: VALIDATED

    Source sequence(s)
    AL807382
    Consensus CDS
    CCDS51231.1
    UniProtKB/Swiss-Prot
    A6PWV3, Q9DAG1
    Related
    ENSMUSP00000102725.2, ENSMUST00000107108.8
    Conserved Domains (1) summary
    pfam15005
    Location:23164
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    92032555..92035462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320383.2XP_017175872.1  izumo sperm-egg fusion protein 3 isoform X1

    Conserved Domains (1) summary
    pfam15005
    Location:23164
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

RNA

  1. XR_003955008.1 RNA Sequence

  2. XR_003955009.1 RNA Sequence

  3. XR_004941954.1 RNA Sequence

  4. XR_003955010.1 RNA Sequence