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MIR550A1 microRNA 550a-1 [ Homo sapiens (human) ]

Gene ID: 693133, updated on 2-Nov-2024

Summary

Official Symbol
MIR550A1provided by HGNC
Official Full Name
microRNA 550a-1provided by HGNC
Primary source
HGNC:HGNC:32804
See related
Ensembl:ENSG00000207771 miRBase:MI0003600; AllianceGenome:HGNC:32804
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIR550-1; MIRN550-1; mir-550a-1; hsa-mir-550a-1
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR550A1 in Genome Data Viewer
Location:
7p14.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (30289794..30289890)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (30427487..30427583)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (30329410..30329506)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25806 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18059 Neighboring gene uncharacterized LOC105375217 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25807 Neighboring gene uncharacterized LOC124901607 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25808 Neighboring gene uncharacterized LOC105375218 Neighboring gene HNF1 motif-containing MPRA enhancer 259 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25809 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18060 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18061 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18062 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18063 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18064 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18065 Neighboring gene microRNA 550b-1 Neighboring gene zinc and ring finger 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:30358457-30358625 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25810 Neighboring gene Sharpr-MPRA regulatory region 6335 Neighboring gene uncharacterized protein DKFZp586I1420 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr7:30430683-30431301 Neighboring gene long intergenic non-protein coding RNA 1176

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_030319.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC006978
    Related
    ENST00000385037.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    30289794..30289890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    30427487..30427583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)