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Cnppd1 cyclin Pas1/PHO80 domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 69171, updated on 26-Sep-2022

Summary

Official Symbol
Cnppd1provided by MGI
Official Full Name
cyclin Pas1/PHO80 domain containing 1provided by MGI
Primary source
MGI:MGI:1916421
See related
Ensembl:ENSMUSG00000033159 AllianceGenome:MGI:1916421
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810031K17Rik
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Orthologous to human CNPPD1 (cyclin Pas1/PHO80 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 27.7), colon adult (RPKM 22.0) and 28 other tissues See more
Orthologs
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Genomic context

See Cnppd1 in Genome Data Viewer
Location:
1; 1 C4
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (75112406..75119374, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (75135762..75142744, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene non-homologous end joining factor 1 Neighboring gene solute carrier family 23 (nucleobase transporters), member 3 Neighboring gene reticulophagy regulator family member 2 Neighboring gene zinc finger, AN1 type domain 2B Neighboring gene ATP-binding cassette, sub-family B (MDR/TAP), member 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of cyclin-dependent protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356264.1NP_001343193.1  protein CNPPD1

    Status: VALIDATED

    Source sequence(s)
    AC173548, AK159252, BE987844, CA562223
    Consensus CDS
    CCDS15063.1
    UniProtKB/Swiss-Prot
    Q3TE87
    Related
    ENSMUSP00000140289.2, ENSMUST00000190679.7
    Conserved Domains (1) summary
    cl00050
    Location:81174
    CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
  2. NM_026977.3NP_081253.1  protein CNPPD1

    See identical proteins and their annotated locations for NP_081253.1

    Status: VALIDATED

    Source sequence(s)
    AC173548, AK145962, BE987844
    Consensus CDS
    CCDS15063.1
    UniProtKB/Swiss-Prot
    Q3TE87, Q8K158
    Related
    ENSMUSP00000044799.6, ENSMUST00000041213.12
    Conserved Domains (1) summary
    cl00050
    Location:81174
    CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    75112406..75119374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496542.4XP_006496605.1  protein CNPPD1 isoform X1

    See identical proteins and their annotated locations for XP_006496605.1

    UniProtKB/Swiss-Prot
    Q3TE87, Q8K158
    Conserved Domains (1) summary
    cl00050
    Location:81174
    CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
  2. XM_006496541.4XP_006496604.1  protein CNPPD1 isoform X1

    See identical proteins and their annotated locations for XP_006496604.1

    UniProtKB/Swiss-Prot
    Q3TE87, Q8K158
    Conserved Domains (1) summary
    cl00050
    Location:81174
    CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...