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Lmtk3 lemur tyrosine kinase 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 691056, updated on 5-Mar-2024

Summary

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Symbol
Lmtk3provided by RGD
Full Name
lemur tyrosine kinase 3provided by RGD
Primary source
RGD:1588641
See related
Ensembl:ENSRNOG00000021048 AllianceGenome:RGD:1588641
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human LMTK3 (lemur tyrosine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 43.2), Uterus (RPKM 3.0) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
1q22
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (105397504..105417146)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (96261058..96280362)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (101773206..101792420)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83, member E Neighboring gene sperm acrosome associated 4 Neighboring gene sulfotransferase family 2B member 1 Neighboring gene uncharacterized LOC134483107 Neighboring gene cytohesin 2 Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Docking motif-guided mapping of the interactome of protein phosphatase-1. Hendrickx A, et al. Chem Biol, 2009 Apr 24. PMID 19389623
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • AC095693.1

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine/threonine-protein kinase LMTK3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    105397504..105417146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039100954.2 → XP_038956882.1  serine/threonine-protein kinase LMTK3 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:148 → 423
    PKc_like; Protein Kinases, catalytic domain

  2. XM_039100951.2 → XP_038956879.1  serine/threonine-protein kinase LMTK3 isoform X1

    Conserved Domains (1) summary
    cl21453
    Location:174 → 449
    PKc_like; Protein Kinases, catalytic domain

  3. XM_008759459.4 → XP_008757681.1  serine/threonine-protein kinase LMTK3 isoform X2

    UniProtKB/TrEMBL
    F1LSB5
    Related
    ENSRNOP00000061430.4
    Conserved Domains (2) summary
    pfam07714
    Location:159 → 434
    Pkinase_Tyr; Protein tyrosine kinase
    cl21453
    Location:161 → 436
    PKc_like; Protein Kinases, catalytic domain

  4. XM_039100953.2 → XP_038956881.1  serine/threonine-protein kinase LMTK3 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:148 → 423
    PKc_like; Protein Kinases, catalytic domain

  5. XM_039100952.2 → XP_038956880.1  serine/threonine-protein kinase LMTK3 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:148 → 423
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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