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Oxa1l oxidase assembly 1-like [ Mus musculus (house mouse) ]

Gene ID: 69089, updated on 9-Mar-2023

Summary

Official Symbol
Oxa1lprovided by MGI
Official Full Name
oxidase assembly 1-likeprovided by MGI
Primary source
MGI:MGI:1916339
See related
Ensembl:ENSMUSG00000000959 AllianceGenome:MGI:1916339
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810020M02Rik
Summary
Predicted to enable membrane insertase activity; mitochondrial ribosome binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including mitochondrion organization; negative regulation of ATPase activity; and protein tetramerization. Located in mitochondrial inner membrane. Orthologous to human OXA1L (OXA1L mitochondrial inner membrane protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 141.2), ovary adult (RPKM 84.6) and 28 other tissues See more
Orthologs
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Genomic context

See Oxa1l in Genome Data Viewer
Location:
14; 14 C2
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (54598298..54607126)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (54360841..54369669)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene 43305 Neighboring gene eukaryotic translation initiation factor 4H pseudogene Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 Neighboring gene mitochondrial ribosomal protein L52 Neighboring gene matrix metallopeptidase 14 (membrane-inserted)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables membrane insertase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mitochondrial ribosome binding ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane HDA PubMed 
located_in mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial inner membrane protein OXA1L
Names
OXA1-like protein
oxidase assembly 1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026936.4NP_081212.1  mitochondrial inner membrane protein OXA1L

    See identical proteins and their annotated locations for NP_081212.1

    Status: VALIDATED

    Source sequence(s)
    AC206013
    Consensus CDS
    CCDS27086.1
    UniProtKB/Swiss-Prot
    Q8BGA9, Q9D8X7
    Related
    ENSMUSP00000000985.6, ENSMUST00000000985.7
    Conserved Domains (1) summary
    COG0706
    Location:74324
    YidC; Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins [Cell wall/membrane/envelope biogenesis]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    54598298..54607126
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)