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Lyzl4 lysozyme-like 4 [ Mus musculus (house mouse) ]

Gene ID: 69032, updated on 31-Jan-2019

Summary

Official Symbol
Lyzl4provided by MGI
Official Full Name
lysozyme-like 4provided by MGI
Primary source
MGI:MGI:1916282
See related
Ensembl:ENSMUSG00000032530
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lyc4; Lyza; AI504271; 1810009N24Rik
Expression
Restricted expression toward testis adult (RPKM 38.8) See more
Orthologs

Genomic context

See Lyzl4 in Genome Data Viewer
Location:
9; 9 F4
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (121577841..121641566, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (121486961..121550684, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene cholecystokinin Neighboring gene predicted gene, 38661 Neighboring gene lysozyme-like 4, opposite strand Neighboring gene vasoactive intestinal peptide receptor 1 Neighboring gene SEC22 homolog C, vesicle trafficking protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
lysozyme activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
defense response to Gram-negative bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NOT defense response to bacterium IDA
Inferred from Direct Assay
more info
PubMed 
fertilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
single fertilization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
acrosomal vesicle IDA
Inferred from Direct Assay
more info
PubMed 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cilium IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
motile cilium IEA
Inferred from Electronic Annotation
more info
 
sperm flagellum IDA
Inferred from Direct Assay
more info
PubMed 
sperm flagellum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
lysozyme-like protein 4
Names
lysozyme a

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357346.1NP_001344275.1  lysozyme-like protein 4 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC131660, AK007412, AV269508
    Conserved Domains (1) summary
    cd00119
    Location:59179
    LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...
  2. NM_026915.3NP_081191.1  lysozyme-like protein 4 isoform 2 precursor

    See identical proteins and their annotated locations for NP_081191.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC131660, AC159810
    Consensus CDS
    CCDS23632.1
    UniProtKB/Swiss-Prot
    Q9D925
    UniProtKB/TrEMBL
    Q78ID0
    Related
    ENSMUSP00000076887.3, ENSMUST00000077706.9
    Conserved Domains (1) summary
    cd00119
    Location:21141
    LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    121577841..121641566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512248.2XP_006512311.1  lysozyme-like protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006512311.1

    UniProtKB/Swiss-Prot
    Q9D925
    UniProtKB/TrEMBL
    Q78ID0
    Related
    ENSMUSP00000113034.1, ENSMUST00000120918.7
    Conserved Domains (1) summary
    cd00119
    Location:21141
    LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...
  2. XM_017313557.1XP_017169046.1  lysozyme-like protein 4 isoform X1

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