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Fpr2 formyl peptide receptor 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690158, updated on 3-Jun-2018
Official Symbol
Fpr2provided by RGD
Official Full Name
formyl peptide receptor 2provided by RGD
Primary source
RGD:1584013
See related
Ensembl:ENSRNOG00000042605
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fprl1; Fpr-rs2
Expression
Biased expression in Spleen (RPKM 2.6), Lung (RPKM 1.5) and 2 other tissues See more
See Fpr2 in Genome Data Viewer
Location:
1q12
Exon count:
2
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (59800558..59809507, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (60719375..60727932, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene hyaluronan synthase 1 Neighboring gene uncharacterized LOC108349528 Neighboring gene formyl peptide receptor 1 Neighboring gene formyl peptide receptor, related sequence 2-like Neighboring gene lysophospholipase-like protein 1 pseudogene

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
G-protein coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
N-formyl peptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
N-formyl peptide receptor activity ISO
Inferred from Sequence Orthology
more info
 
RAGE receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
cargo receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
complement receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
scavenger receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
scavenger receptor binding ISO
Inferred from Sequence Orthology
more info
 
signaling receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
astrocyte activation IGI
Inferred from Genetic Interaction
more info
PubMed 
calcium-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
cellular response to amyloid-beta IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to amyloid-beta ISO
Inferred from Sequence Orthology
more info
 
complement receptor mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
leukocyte migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microglial cell activation IGI
Inferred from Genetic Interaction
more info
PubMed 
phospholipase C-activating G-protein coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phospholipase C-activating G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of 1-phosphatidylinositol-3-kinase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of ERK1 and ERK2 cascade IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of ERK1 and ERK2 cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of monocyte chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of superoxide anion generation ISO
Inferred from Sequence Orthology
more info
 
receptor-mediated endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with cytoplasm ISO
Inferred from Sequence Orthology
more info
 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
formyl peptide receptor 2-like; formyl peptide receptor, related sequence 2
Names
formyl peptide receptor, related sequence 2-like
formyl peptide receptor-like 1

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    59800558..59809507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001073508.5XP_001073508.1  formyl peptide receptor 2-like

    See identical proteins and their annotated locations for XP_001073508.1

    UniProtKB/TrEMBL
    F1M670
    Related
    ENSRNOP00000061936.3, ENSRNOT00000064917.3
    Conserved Domains (1) summary
    pfam00001
    Location:43302
    7tm_1; 7 transmembrane receptor (rhodopsin family)

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    54955259..54964212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003753185.4XP_003753233.1  formyl peptide receptor 2-like

    See identical proteins and their annotated locations for XP_003753233.1

    UniProtKB/TrEMBL
    F1M670
    Conserved Domains (1) summary
    pfam00001
    Location:43302
    7tm_1; 7 transmembrane receptor (rhodopsin family)
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