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Atg2a autophagy related 2A [ Rattus norvegicus (Norway rat) ]

Gene ID: 689688, updated on 30-Sep-2021

Summary

Official Symbol
Atg2aprovided by RGD
Official Full Name
autophagy related 2Aprovided by RGD
Primary source
RGD:1589890
See related
EnsemblRapid:ENSRNOG00000060707
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Kidney (RPKM 51.1), Adrenal (RPKM 46.5) and 9 other tissues See more
Orthologs
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Genomic context

See Atg2a in Genome Data Viewer
Location:
1q43
Exon count:
40
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (203542559..203562242)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (221612584..221632291)

Chromosome 1 - NC_051336.1Genomic Context describing neighboring genes Neighboring gene membrane anchored junction protein Neighboring gene protein phosphatase 2, regulatory subunit B', beta Neighboring gene glycoprotein hormone subunit alpha 2 Neighboring gene microRNA 194-2 Neighboring gene microRNA 192

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphatidylinositol-3-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in autophagosome assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in late nucleophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in piecemeal microautophagy of the nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in reticulophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in extrinsic component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 
is_active_in phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in phagophore assembly site membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
autophagy-related protein 2 homolog A
Names
ATG2 autophagy related 2 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109545.1NP_001103015.1  autophagy-related protein 2 homolog A

    See identical proteins and their annotated locations for NP_001103015.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473953
    UniProtKB/TrEMBL
    D3ZT64
    Related
    ENSRNOP00000073173.1, ENSRNOT00000090100.2
    Conserved Domains (2) summary
    pfam09333
    Location:18171910
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:14111
    Chorein_N; N-terminal region of Chorein or VPS13

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051336.1 Reference mRatBN7.2 Primary Assembly

    Range
    203542559..203562242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005492572.1 RNA Sequence

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