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Paqr6 progestin and adipoQ receptor family member VI [ Mus musculus (house mouse) ]

Gene ID: 68957, updated on 30-Apr-2024

Summary

Official Symbol
Paqr6provided by MGI
Official Full Name
progestin and adipoQ receptor family member VIprovided by MGI
Primary source
MGI:MGI:1916207
See related
Ensembl:ENSMUSG00000041423 AllianceGenome:MGI:1916207
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500001B10Rik
Summary
Predicted to enable signaling receptor activity. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including gut; lung; pharyngo-tympanic tube; ventricular layer; and vibrissa. Orthologous to human PAQR6 (progestin and adipoQ receptor family member 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 11.5), ovary adult (RPKM 8.9) and 19 other tissues See more
Orthologs
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Genomic context

See Paqr6 in Genome Data Viewer
Location:
3 F1; 3 38.81 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (88271376..88275848)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (88364072..88368541)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 79 Neighboring gene SMG5 nonsense mediated mRNA decay factor Neighboring gene bone gamma-carboxyglutamate protein 3 Neighboring gene predicted gene, 21956

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
membrane progestin receptor delta
Names
mPR delta
membrane progesterone P4 receptor delta
membrane progesterone receptor delta
progesterone and adipoQ receptor family member 6
progestin and adipoQ receptor family member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310597.1NP_001297526.1  membrane progestin receptor delta isoform 2

    See identical proteins and their annotated locations for NP_001297526.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate in-frame exons in its central coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AK139144, BE996278
    Consensus CDS
    CCDS79941.1
    UniProtKB/TrEMBL
    D3Z1S5
    Related
    ENSMUSP00000119656.2, ENSMUST00000147948.8
    Conserved Domains (1) summary
    cl03831
    Location:71161
    HlyIII; Haemolysin-III related
  2. NM_001404108.1NP_001391037.1  membrane progestin receptor delta isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC102388
    UniProtKB/Swiss-Prot
    Q3UTT0, Q6TCG5, Q8CF56
    UniProtKB/TrEMBL
    Q0VBT6
  3. NM_001404109.1NP_001391038.1  membrane progestin receptor delta isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC102388
  4. NM_001404110.1NP_001391039.1  membrane progestin receptor delta isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC102388
  5. NM_198410.3NP_940802.1  membrane progestin receptor delta isoform 1

    See identical proteins and their annotated locations for NP_940802.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AI607833, AK139144
    Consensus CDS
    CCDS17471.1
    UniProtKB/Swiss-Prot
    Q3UTT0, Q6TCG5, Q8CF56
    UniProtKB/TrEMBL
    Q0VBT6
    Related
    ENSMUSP00000114166.2, ENSMUST00000147991.2
    Conserved Domains (1) summary
    pfam03006
    Location:43271
    HlyIII; Haemolysin-III related

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    88271376..88275848
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502009.5XP_006502072.1  membrane progestin receptor delta isoform X2

    Conserved Domains (1) summary
    pfam03006
    Location:58311
    HlyIII; Haemolysin-III related
  2. XM_006502010.3XP_006502073.1  membrane progestin receptor delta isoform X3

    See identical proteins and their annotated locations for XP_006502073.1

    Conserved Domains (1) summary
    pfam03006
    Location:43296
    HlyIII; Haemolysin-III related