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Best4 bestrophin 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 689103, updated on 2-Oct-2018

Summary

Official Symbol
Best4provided by RGD
Official Full Name
bestrophin 4provided by RGD
Primary source
RGD:1596200
See related
Ensembl:ENSRNOG00000018749
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Spleen (RPKM 1.3), Thymus (RPKM 1.3) and 8 other tissues See more
Orthologs

Genomic context

See Best4 in Genome Data Viewer
Location:
5q36
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (136013978..136017742)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (139806969..139810707)

Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene BTB domain containing 19 Neighboring gene Tctex1 domain containing 4 Neighboring gene polo-like kinase 3 Neighboring gene ribosomal protein S8 Neighboring gene kinesin family member 2C

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
chloride channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
chloride channel complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
bestrophin-4; similar to vitelliform macular dystrophy 2-like 2

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

    Range
    136013978..136017742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001066317.3XP_001066317.1  bestrophin-4

    See identical proteins and their annotated locations for XP_001066317.1

    UniProtKB/TrEMBL
    D3ZX44
    Related
    ENSRNOP00000025348.5, ENSRNOT00000025346.6
    Conserved Domains (1) summary
    pfam01062
    Location:8316
    Bestrophin; Bestrophin, RFP-TM, chloride channel

Alternate Rn_Celera

Genomic

  1. AC_000073.1 Alternate Rn_Celera

    Range
    129144974..129148738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002726582.3XP_002726628.1  bestrophin-4

    See identical proteins and their annotated locations for XP_002726628.1

    UniProtKB/TrEMBL
    D3ZX44
    Conserved Domains (1) summary
    pfam01062
    Location:8316
    Bestrophin; Bestrophin, RFP-TM, chloride channel
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