Lin28b lin-28 RNA binding posttranscriptional regulator B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lin28bprovided by RGD
Official Full Name: lin-28 RNA binding posttranscriptional regulator Bprovided by RGD
Primary source: RGD:1597432
See related: Ensembl:ENSRNOG00000025938 AllianceGenome:RGD:1597432
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable mRNA binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in RNA metabolic process and positive regulation of macromolecule metabolic process. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human LIN28B (lin-28 homolog B). [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in Testes (RPKM 10.0), Brain (RPKM 9.4) and 2 other tissues See more
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (50447700..50547135, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (48865329..48964769, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (50482536..50580273, complement)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA 3'-end processing	ISO Inferred from Sequence Orthology more info
involved_in RNA destabilization	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in miRNA catabolic process	IEA Inferred from Electronic Annotation more info
involved_in miRNA catabolic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of pre-miRNA processing	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of primary miRNA processing	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of miRNA catabolic process	ISO Inferred from Sequence Orthology more info
involved_in post-transcriptional regulation of gene expression	IEA Inferred from Electronic Annotation more info
involved_in pre-miRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in pre-miRNA processing	IEA Inferred from Electronic Annotation more info
involved_in pre-miRNA processing	ISO Inferred from Sequence Orthology more info
involved_in regulation of miRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

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