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Arv1 ARV1 homolog, fatty acid homeostasis modulator [ Mus musculus (house mouse) ]

Gene ID: 68865, updated on 12-May-2024

Summary

Official Symbol
Arv1provided by MGI
Official Full Name
ARV1 homolog, fatty acid homeostasis modulatorprovided by MGI
Primary source
MGI:MGI:1916115
See related
Ensembl:ENSMUSG00000031982 AllianceGenome:MGI:1916115
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110067L22Rik
Summary
Acts upstream of or within bile acid metabolic process and regulation of cholesterol metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus and cortical endoplasmic reticulum. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 38. Orthologous to human ARV1 (ARV1 homolog, fatty acid homeostasis modulator). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 10.0), ovary adult (RPKM 7.3) and 28 other tissues See more
Orthologs
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Genomic context

See Arv1 in Genome Data Viewer
Location:
8 E2; 8 72.81 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (125448765..125469533)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (124722026..124742794)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 13 Neighboring gene predicted gene, 46058 Neighboring gene predicted gene, 30273 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:127246145-127246328 Neighboring gene family with sequence similarity 89, member A Neighboring gene general transcription factor IIB pseudogene Neighboring gene predicted gene, 46059

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (4)  1 citation

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cortical endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368372.1NP_001355301.1  protein ARV1

    Status: VALIDATED

    Source sequence(s)
    AC151736
    Consensus CDS
    CCDS22774.1
    UniProtKB/Swiss-Prot
    Q8BY08, Q9D0U9
    UniProtKB/TrEMBL
    Q0VBH5
    Conserved Domains (1) summary
    pfam04161
    Location:28217
    Arv1; Arv1-like family
  2. NM_026855.5NP_081131.1  protein ARV1

    See identical proteins and their annotated locations for NP_081131.1

    Status: VALIDATED

    Source sequence(s)
    AC151736
    Consensus CDS
    CCDS22774.1
    UniProtKB/Swiss-Prot
    Q8BY08, Q9D0U9
    UniProtKB/TrEMBL
    Q0VBH5
    Related
    ENSMUSP00000034463.4, ENSMUST00000034463.4
    Conserved Domains (1) summary
    pfam04161
    Location:28217
    Arv1; Arv1-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    125448765..125469533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248496.3XP_011246798.1  protein ARV1 isoform X1

    See identical proteins and their annotated locations for XP_011246798.1

    UniProtKB/Swiss-Prot
    Q8BY08, Q9D0U9
    UniProtKB/TrEMBL
    Q0VBH5
    Conserved Domains (1) summary
    pfam04161
    Location:28217
    Arv1; Arv1-like family
  2. XM_006531337.4XP_006531400.1  protein ARV1 isoform X1

    See identical proteins and their annotated locations for XP_006531400.1

    UniProtKB/Swiss-Prot
    Q8BY08, Q9D0U9
    UniProtKB/TrEMBL
    Q0VBH5
    Conserved Domains (1) summary
    pfam04161
    Location:28217
    Arv1; Arv1-like family