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Tmem214 transmembrane protein 214 [ Mus musculus (house mouse) ]

Gene ID: 68796, updated on 26-Sep-2022

Summary

Official Symbol
Tmem214provided by MGI
Official Full Name
transmembrane protein 214provided by MGI
Primary source
MGI:MGI:1916046
See related
Ensembl:ENSMUSG00000038828 AllianceGenome:MGI:1916046
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110039B18Rik; 4921530J21Rik
Summary
Predicted to act upstream of or within apoptotic process. Predicted to be located in cytoplasmic microtubule and cytosol. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in axial skeleton; chondrocranium; otic capsule; and rib. Orthologous to human TMEM214 (transmembrane protein 214). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 69.9), testis adult (RPKM 47.1) and 28 other tissues See more
Orthologs
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Genomic context

See Tmem214 in Genome Data Viewer
Location:
5; 5 B1
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31026923..31034813)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (30869579..30877469)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene dihydropyrimidinase-like 5 Neighboring gene predicted gene, 46907 Neighboring gene microtubule-associated protein, RP/EB family, member 3 Neighboring gene nuclear encoded tRNA alanine 15 (anticodon AGC) Neighboring gene nuclear encoded tRNA tyrosine 9 (anticodon GTA) Neighboring gene predicted gene, 35795 Neighboring gene ATP/GTP binding protein-like 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20254

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144525.4NP_653108.2  transmembrane protein 214

    See identical proteins and their annotated locations for NP_653108.2

    Status: VALIDATED

    Source sequence(s)
    AC109606, AK034883
    Consensus CDS
    CCDS19164.1
    UniProtKB/Swiss-Prot
    Q8BM55, Q8VC05
    Related
    ENSMUSP00000144615.2, ENSMUST00000201203.4
    Conserved Domains (1) summary
    pfam10151
    Location:217683
    DUF2359; uncharacterized conserved protein (DUF2359)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    31026923..31034813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165466.1XP_036021359.1  transmembrane protein 214 isoform X1

    Related
    ENSMUST00000202008.2
    Conserved Domains (1) summary
    pfam10151
    Location:1378
    TMEM214; C-terminal, caspase 4 activator