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Phtf2 putative homeodomain transcription factor 2 [ Mus musculus (house mouse) ]

Gene ID: 68770, updated on 26-Sep-2022

Summary

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Official Symbol
Phtf2provided by MGI
Official Full Name
putative homeodomain transcription factor 2provided by MGI
Primary source
MGI:MGI:1916020
See related
Ensembl:ENSMUSG00000039987 AllianceGenome:MGI:1916020
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110054G21Rik; 9530062N20Rik
Summary
Predicted to be located in endoplasmic reticulum. Is expressed in brain. Orthologous to human PHTF2 (putative homeodomain transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in heart adult (RPKM 6.9), CNS E18 (RPKM 5.0) and 22 other tissues See more
Orthologs
human all
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Genomic context

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See Phtf2 in Genome Data Viewer
Location:
5; 5 A3
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (20963662..21087122, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (20758664..20882137, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene membrane associated guanylate kinase, WW and PDZ domain containing 2 Neighboring gene mitochondrial ribosomal protein S36 pseudogene Neighboring gene predicted gene, 52763 Neighboring gene ribosomal protein L31, pseudogene 5 Neighboring gene predicted gene, 52806 Neighboring gene RIKEN cDNA A630072M18 gene Neighboring gene predicted gene, 42219 Neighboring gene transmembrane protein 60 Neighboring gene round spermatid basic protein 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  4. A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Thompson CL, et al. Neuron, 2014 Jul 16. PMID 24952961, Free PMC Article
  5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

See all (21) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein PHTF2; putative homeodomain transcription factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172992.3 → NP_766580.3  protein PHTF2

    See identical proteins and their annotated locations for NP_766580.3

    Status: VALIDATED

    Source sequence(s)
    AK004246, AK037021, AK042382, AK151762, CB245749
    Consensus CDS
    CCDS51426.1
    UniProtKB/Swiss-Prot
    Q8CB19
    UniProtKB/TrEMBL
    A0A0R4J1Q1, Q8C9D2
    Related
    ENSMUSP00000114087.2, ENSMUST00000118174.8
    Conserved Domains (1) summary
    pfam12129
    Location:5 → 152
    Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    20963662..21087122 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006535801.3 → XP_006535864.1  putative homeodomain transcription factor 2 isoform X3

    Conserved Domains (1) summary
    pfam12129
    Location:5 → 154
    Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

  2. XM_036165461.1 → XP_036021354.1  putative homeodomain transcription factor 2 isoform X2

    Conserved Domains (1) summary
    pfam12129
    Location:5 → 158
    Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

  3. XM_036165460.1 → XP_036021353.1  putative homeodomain transcription factor 2 isoform X1

    Conserved Domains (1) summary
    pfam12129
    Location:5 → 158
    Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

  4. XM_030254785.2 → XP_030110645.1  putative homeodomain transcription factor 2 isoform X6

  5. XM_036165462.1 → XP_036021355.1  putative homeodomain transcription factor 2 isoform X4

    Conserved Domains (1) summary
    pfam12129
    Location:1 → 17
    Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

  6. XM_036165463.1 → XP_036021356.1  putative homeodomain transcription factor 2 isoform X4

    Conserved Domains (1) summary
    pfam12129
    Location:1 → 17
    Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

  7. XM_036165465.1 → XP_036021358.1  putative homeodomain transcription factor 2 isoform X6

  8. XM_036165464.1 → XP_036021357.1  putative homeodomain transcription factor 2 isoform X5

    Conserved Domains (1) summary
    pfam12129
    Location:5 → 154
    Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

RNA

  1. XR_003955706.2 RNA Sequence

  2. XR_004942555.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CB19.2 GenPept UniProtKB/Swiss-Prot:Q8CB19

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