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Vps37d VPS37D subunit of ESCRT-I [ Rattus norvegicus (Norway rat) ]

Gene ID: 687208, updated on 10-Feb-2026
Official Symbol
Vps37dprovided by RGD
Official Full Name
VPS37D subunit of ESCRT-Iprovided by RGD
Primary source
RGD:1587769
See related
Ensembl:ENSRNOG00000048699 AllianceGenome:RGD:1587769
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT I complex. Orthologous to human VPS37D (VPS37D subunit of ESCRT-I). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Kidney (RPKM 63.5), Brain (RPKM 36.6) and 6 other tissues See more
Orthologs
all
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See Vps37d in Genome Data Viewer
Location:
12q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (27245755..27251214)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (21609210..21614669)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (24651342..24656793)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene transducin (beta)-like 2 Neighboring gene MLX interacting protein-like Neighboring gene DnaJ heat shock protein family (Hsp40) member C30 Neighboring gene small Cajal body-specific RNA 20 Neighboring gene BUD23, rRNA methyltransferase and ribosome maturation factor

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Agromayor M, et al. Structure, 2012 Mar 7. PMID 22405001, Free PMC Article
  2. Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. Morita E, et al. Cell Host Microbe, 2007 Jul 12. PMID 18005716, Free PMC Article
  3. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  4. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
  5. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC188182

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein targeting to vacuole IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ESCRT I complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ESCRT I complex IEA
Inferred from Electronic Annotation
more info
  
part_of ESCRT I complex ISO
Inferred from Sequence Orthology
more info
  
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
vacuolar protein sorting-associated protein 37D
Names
VPS37D, ESCRT-I subunit
vacuolar protein sorting 37 homolog D
vacuolar protein sorting 37D

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128193.2 → NP_001121665.1  vacuolar protein sorting-associated protein 37D

    See identical proteins and their annotated locations for NP_001121665.1

    Status: PROVISIONAL

    Source sequence(s)
    BC166560
    UniProtKB/TrEMBL
    B2GV76, M0RC56
    Related
    ENSRNOP00000067165.1, ENSRNOT00000071569.4
    Conserved Domains (2) summary
    PTZ00449
    Location:198 → 259
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam07200
    Location:22 → 165
    Mod_r; Modifier of rudimentary (Mod(r)) protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    27245755..27251214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089755.2 → XP_038945683.1  vacuolar protein sorting-associated protein 37D isoform X1

    UniProtKB/TrEMBL
    A0ABK0KZ80
    Related
    ENSRNOP00000100618.1, ENSRNOT00000169920.1
    Conserved Domains (2) summary
    PTZ00449
    Location:191 → 252
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam07200
    Location:39 → 158
    Mod_r; Modifier of rudimentary (Mod(r)) protein
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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