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Kansl1l KAT8 regulatory NSL complex subunit 1-like [ Mus musculus (house mouse) ]

Gene ID: 68691, updated on 26-Sep-2022

Summary

Official Symbol
Kansl1lprovided by MGI
Official Full Name
KAT8 regulatory NSL complex subunit 1-likeprovided by MGI
Primary source
MGI:MGI:1915941
See related
Ensembl:ENSMUSG00000026004 AllianceGenome:MGI:1915941
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA4189; 1190030G24; 1110028C15Rik; C430010P07Rik
Summary
Predicted to enable histone acetyltransferase binding activity. Predicted to be part of NSL complex. Orthologous to human KANSL1L (KAT8 regulatory NSL complex subunit 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 1.9), bladder adult (RPKM 1.6) and 25 other tissues See more
Orthologs
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Genomic context

See Kansl1l in Genome Data Viewer
Location:
1; 1 C3
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (66758402..66856754, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (66719243..66817596, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene microtubule-associated protein 2 Neighboring gene predicted gene, 25411 Neighboring gene unc-80, NALCN activator Neighboring gene predicted gene, 39655 Neighboring gene ribulose-5-phosphate-3-epimerase Neighboring gene predicted gene, 46093 Neighboring gene heat shock protein 1 (chaperonin) pseudogene Neighboring gene predicted gene 15793 Neighboring gene predicted gene, 27934 Neighboring gene acyl-Coenzyme A dehydrogenase, long-chain

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Homology

Clone Names

  • KIAA4189, MGC175997, AC118589.2

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables histone acetyltransferase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of NSL complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
KAT8 regulatory NSL complex subunit 1-like protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122738.1NP_001116210.1  KAT8 regulatory NSL complex subunit 1-like protein isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
    Source sequence(s)
    AK082897, AK138707, AK145440, BB793048, CJ177470
    UniProtKB/Swiss-Prot
    Q5DTI6
    Conserved Domains (1) summary
    pfam15275
    Location:764884
    PEHE; PEHE domain
  2. NM_001357156.1NP_001344085.1  KAT8 regulatory NSL complex subunit 1-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC118589, AC124389
    Consensus CDS
    CCDS35603.1
    Conserved Domains (1) summary
    pfam15275
    Location:755875
    PEHE; PEHE domain
  3. NM_001357157.1NP_001344086.1  KAT8 regulatory NSL complex subunit 1-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC118589, AC124389
    Conserved Domains (1) summary
    pfam15275
    Location:754845
    PEHE; PEHE domain
  4. NM_001368830.1NP_001355759.1  KAT8 regulatory NSL complex subunit 1-like protein isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC118589, AC124389
    Conserved Domains (1) summary
    pfam15275
    Location:720811
    PEHE; PEHE domain
  5. NM_177645.4NP_808313.3  KAT8 regulatory NSL complex subunit 1-like protein isoform 2

    See identical proteins and their annotated locations for NP_808313.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame segment in the 3' CDS, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AK082897, AK138707, AK145440, AK220534, BB793048, CJ177470
    Consensus CDS
    CCDS35603.1
    UniProtKB/Swiss-Prot
    Q5DTI6
    Related
    ENSMUSP00000063843.4, ENSMUST00000068168.10
    Conserved Domains (1) summary
    pfam15275
    Location:755875
    PEHE; PEHE domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    66758402..66856754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322317.2XP_017177806.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X12

    Conserved Domains (1) summary
    pfam15275
    Location:754845
    PEHE; PEHE domain
  2. XM_017322311.2XP_017177800.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X5

    Conserved Domains (1) summary
    pfam15275
    Location:798889
    PEHE; PEHE domain
  3. XM_006496241.3XP_006496304.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    See identical proteins and their annotated locations for XP_006496304.1

    UniProtKB/Swiss-Prot
    Q5DTI6, Q8C4R5
    Conserved Domains (1) summary
    pfam15275
    Location:799919
    PEHE; PEHE domain
  4. XM_030242671.2XP_030098531.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X13

    Conserved Domains (1) summary
    pfam15275
    Location:720811
    PEHE; PEHE domain
  5. XM_030242649.2XP_030098509.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    UniProtKB/Swiss-Prot
    Q8C4R5
    Conserved Domains (1) summary
    pfam15275
    Location:799919
    PEHE; PEHE domain
  6. XM_030242665.2XP_030098525.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X9

    Conserved Domains (1) summary
    pfam15275
    Location:763883
    PEHE; PEHE domain
  7. XM_036153352.1XP_036009245.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X8

    Conserved Domains (1) summary
    pfam15275
    Location:764884
    PEHE; PEHE domain
  8. XM_011238574.3XP_011236876.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011236876.1

    Conserved Domains (1) summary
    pfam15275
    Location:834954
    PEHE; PEHE domain
  9. XM_036153358.1XP_036009251.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X10

    Conserved Domains (1) summary
    pfam15275
    Location:755875
    PEHE; PEHE domain
  10. XM_036153341.1XP_036009234.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    UniProtKB/Swiss-Prot
    Q8C4R5
    Conserved Domains (1) summary
    pfam15275
    Location:799919
    PEHE; PEHE domain
  11. XM_011238571.3XP_011236873.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011236873.1

    Conserved Domains (1) summary
    pfam15275
    Location:834954
    PEHE; PEHE domain
  12. XM_017322316.2XP_017177805.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X11

    Conserved Domains (1) summary
    pfam15275
    Location:755846
    PEHE; PEHE domain
  13. XM_011238578.2XP_011236880.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X4

    Conserved Domains (1) summary
    pfam15275
    Location:799890
    PEHE; PEHE domain
  14. XM_011238580.2XP_011236882.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X7

    Conserved Domains (1) summary
    pfam15275
    Location:789880
    PEHE; PEHE domain
  15. XM_011238579.2XP_011236881.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X6

    Conserved Domains (1) summary
    pfam15275
    Location:790881
    PEHE; PEHE domain
  16. XM_011238576.2XP_011236878.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X2

    Conserved Domains (1) summary
    pfam15275
    Location:833924
    PEHE; PEHE domain
  17. XM_011238570.2XP_011236872.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011236872.1

    Conserved Domains (1) summary
    pfam15275
    Location:834954
    PEHE; PEHE domain
  18. XM_036153357.1XP_036009250.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X9

    Conserved Domains (1) summary
    pfam15275
    Location:763883
    PEHE; PEHE domain
  19. XM_036153363.1XP_036009256.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X18

    Related
    ENSMUSP00000118603.2, ENSMUST00000129190.8
    Conserved Domains (1) summary
    pfam15275
    Location:338458
    PEHE; PEHE domain
  20. XM_036153332.1XP_036009225.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    Conserved Domains (1) summary
    pfam15275
    Location:834954
    PEHE; PEHE domain
  21. XM_036153365.1XP_036009258.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X19

    Conserved Domains (1) summary
    pfam15275
    Location:294414
    PEHE; PEHE domain
  22. XM_006496249.3XP_006496312.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X15

    See identical proteins and their annotated locations for XP_006496312.1

    Conserved Domains (1) summary
    pfam15275
    Location:467558
    PEHE; PEHE domain
  23. XM_030242669.2XP_030098529.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X13

    Conserved Domains (1) summary
    pfam15275
    Location:720811
    PEHE; PEHE domain
  24. XM_036153359.1XP_036009252.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X10

    Conserved Domains (1) summary
    pfam15275
    Location:755875
    PEHE; PEHE domain
  25. XM_011238575.3XP_011236877.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011236877.1

    Conserved Domains (1) summary
    pfam15275
    Location:834954
    PEHE; PEHE domain
  26. XM_011238583.3XP_011236885.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X15

    See identical proteins and their annotated locations for XP_011236885.1

    Conserved Domains (1) summary
    pfam15275
    Location:467558
    PEHE; PEHE domain
  27. XM_011238573.3XP_011236875.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011236875.1

    Conserved Domains (1) summary
    pfam15275
    Location:834954
    PEHE; PEHE domain
  28. XM_011238582.4XP_011236884.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X15

    See identical proteins and their annotated locations for XP_011236884.1

    Conserved Domains (1) summary
    pfam15275
    Location:467558
    PEHE; PEHE domain
  29. XM_011238577.4XP_011236879.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    See identical proteins and their annotated locations for XP_011236879.1

    UniProtKB/Swiss-Prot
    Q5DTI6, Q8C4R5
    Conserved Domains (1) summary
    pfam15275
    Location:799919
    PEHE; PEHE domain
  30. XM_011238572.4XP_011236874.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011236874.1

    Conserved Domains (1) summary
    pfam15275
    Location:834954
    PEHE; PEHE domain
  31. XM_011238581.4XP_011236883.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X14

    Related
    ENSMUSP00000109620.2, ENSMUST00000113987.2
  32. XM_011238584.4XP_011236886.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X16

  33. XM_036153362.1XP_036009255.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X17

RNA

  1. XR_001785576.2 RNA Sequence

  2. XR_003946490.2 RNA Sequence

  3. XR_004934169.1 RNA Sequence

  4. XR_004934170.1 RNA Sequence

  5. XR_003946488.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001033526.1: Suppressed sequence

    Description
    NM_001033526.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.