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Svop SV2 related protein [ Mus musculus (house mouse) ]

Gene ID: 68666, updated on 8-May-2024

Summary

Official Symbol
Svopprovided by MGI
Official Full Name
SV2 related proteinprovided by MGI
Primary source
MGI:MGI:1915916
See related
Ensembl:ENSMUSG00000042078 AllianceGenome:MGI:1915916
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
msvop; 1110030H18Rik
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in synaptic vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Orthologous to human SVOP (SV2 related protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 29.0), frontal lobe adult (RPKM 25.8) and 6 other tissues See more
Orthologs
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Genomic context

See Svop in Genome Data Viewer
Location:
5 F; 5 55.94 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (114164974..114229441, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (114026913..114091380, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene slingshot protein phosphatase 1 Neighboring gene predicted gene, 52826 Neighboring gene D-amino acid oxidase Neighboring gene predicted gene 16108 Neighboring gene ubiquitin specific peptidase 30 Neighboring gene legumain pseudogene Neighboring gene STARR-seq mESC enhancer starr_14065 Neighboring gene alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase Neighboring gene uracil DNA glycosylase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (2)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
synaptic vesicle 2-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359214.1NP_001346143.1  synaptic vesicle 2-related protein isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC129080, AC145559
    Conserved Domains (1) summary
    TIGR00898
    Location:12518
    2A0119; cation transport protein
  2. NM_026805.1NP_081081.1  synaptic vesicle 2-related protein isoform 1

    See identical proteins and their annotated locations for NP_081081.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK047764, AK053833, AK082744
    Consensus CDS
    CCDS39220.1
    UniProtKB/Swiss-Prot
    Q6PB56, Q8BFT9, Q8BKY9
    Related
    ENSMUSP00000050730.7, ENSMUST00000058472.13
    Conserved Domains (1) summary
    TIGR00898
    Location:9519
    2A0119; cation transport protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    114164974..114229441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)