Uroc1 urocanate hydratase 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Uroc1provided by RGD
Full Name: urocanate hydratase 1provided by RGD
Primary source: RGD:1587777
See related: Ensembl:ENSRNOG00000043404 AllianceGenome:RGD:1587777
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable urocanate hydratase activity. Predicted to be involved in histidine catabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in urocanase deficiency. Orthologous to human UROC1 (urocanate hydratase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 434.3) See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (124402119..124433787)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (122844933..122876584)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (122244744..122276357)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables urocanate hydratase activity	IBA Inferred from Biological aspect of Ancestor more info
enables urocanate hydratase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in histidine catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in histidine catabolic process	ISO Inferred from Sequence Orthology more info
involved_in histidine catabolic process to glutamate and formamide	IEA Inferred from Electronic Annotation more info
involved_in histidine catabolic process to glutamate and formate	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info

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The following sections contain reference sequences that belong to a specific genome build. Explain