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Jazf1 JAZF zinc finger 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685879, updated on 5-Jan-2022

Summary

Official Symbol
Jazf1provided by RGD
Official Full Name
JAZF zinc finger 1provided by RGD
Primary source
RGD:1589007
See related
Ensembl:ENSRNOG00000027026
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable transcription corepressor activity. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Orthologous to human JAZF1 (JAZF zinc finger 1). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Brain (RPKM 42.4), Thymus (RPKM 41.3) and 9 other tissues See more
Orthologs
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Genomic context

See Jazf1 in Genome Data Viewer
Location:
4q24
Exon count:
7
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (81879501..82183241, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (82834181..83141430, complement)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxyisobutyrate dehydrogenase Neighboring gene uncharacterized LOC120102279 Neighboring gene Tax1 binding protein 1 Neighboring gene serine/arginine-rich splicing factor 7-like Neighboring gene uncharacterized LOC108350711 Neighboring gene uncharacterized LOC120102280 Neighboring gene creatine kinase U-type, mitochondrial-like Neighboring gene small nucleolar RNA SNORA48

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in fibrillar center IEA
Inferred from Electronic Annotation
more info
 
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of transcription repressor complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
juxtaposed with another zinc finger protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    81879501..82183241 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001065610.7XP_001065610.1  juxtaposed with another zinc finger protein 1 isoform X1

    See identical proteins and their annotated locations for XP_001065610.1

    UniProtKB/TrEMBL
    D3ZA80
    Related
    ENSRNOP00000036865.4, ENSRNOT00000039580.5
    Conserved Domains (1) summary
    COG5189
    Location:169230
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
  2. XM_039108679.1XP_038964607.1  juxtaposed with another zinc finger protein 1 isoform X2

    Conserved Domains (1) summary
    COG5189
    Location:105166
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
  3. XM_006236536.4XP_006236598.1  juxtaposed with another zinc finger protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006236598.1

    Conserved Domains (1) summary
    COG5189
    Location:105166
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
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