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Mrps18a mitochondrial ribosomal protein S18A [ Mus musculus (house mouse) ]

Gene ID: 68565, updated on 17-Jun-2024

Summary

Official Symbol
Mrps18aprovided by MGI
Official Full Name
mitochondrial ribosomal protein S18Aprovided by MGI
Primary source
MGI:MGI:1915815
See related
Ensembl:ENSMUSG00000023967 AllianceGenome:MGI:1915815
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110004O20Rik
Summary
Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and pancreas epithelium. Orthologous to human MRPS18A (mitochondrial ribosomal protein S18A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 35.9), kidney adult (RPKM 35.7) and 28 other tissues See more
Orthologs
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Genomic context

See Mrps18a in Genome Data Viewer
Location:
17 C; 17 22.86 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46421930..46439834)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46111004..46128908)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42657 Neighboring gene vascular endothelial growth factor A Neighboring gene STARR-positive B cell enhancer ABC_E5613 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:46210901-46211088 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide K pseudogene Neighboring gene radial spoke head 9 homolog (Chlamydomonas) Neighboring gene MAD2L1 binding protein Neighboring gene STARR-positive B cell enhancer ABC_E5614 Neighboring gene STARR-positive B cell enhancer ABC_E5615 Neighboring gene GTP binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC66832

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables small ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein mL66
Names
28S ribosomal protein S18-3, mitochondrial
28S ribosomal protein S18a, mitochondrial
MRP-S18-3
MRP-S18-a
S18mt-a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026768.3NP_081044.1  large ribosomal subunit protein mL66 precursor

    See identical proteins and their annotated locations for NP_081044.1

    Status: PROVISIONAL

    Source sequence(s)
    AC110562
    Consensus CDS
    CCDS28819.1
    UniProtKB/Swiss-Prot
    Q8R3H2, Q99N85, Q9D1J6
    UniProtKB/TrEMBL
    Q5U5I3
    Related
    ENSMUSP00000024763.4, ENSMUST00000024763.10
    Conserved Domains (1) summary
    pfam01084
    Location:78128
    Ribosomal_S18; Ribosomal protein S18

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    46421930..46439834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)