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SYPL1 synaptophysin like 1 [ Homo sapiens (human) ]

Gene ID: 6856, updated on 13-Mar-2020

Summary

Official Symbol
SYPL1provided by HGNC
Official Full Name
synaptophysin like 1provided by HGNC
Primary source
HGNC:HGNC:11507
See related
Ensembl:ENSG00000008282 MIM:616665
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SYPL; H-SP1
Expression
Ubiquitous expression in thyroid (RPKM 63.3), esophagus (RPKM 56.9) and 25 other tissues See more
Orthologs

Genomic context

See SYPL1 in Genome Data Viewer
Location:
7q22.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (106090362..106112576, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (105730814..105753093, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ataxin 7 like 1 Neighboring gene ribosomal protein L13a pseudogene 16 Neighboring gene cadherin related family member 3 Neighboring gene uncharacterized LOC107986833 Neighboring gene DDB1 and CUL4 associated factor 13 pseudogene 1 Neighboring gene RNA, U6 small nuclear 392, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ46439

Gene Ontology Provided by GOA

Function Evidence Code Pubs
syntaxin-1 binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
chemical synaptic transmission TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
integral component of membrane TAS
Traceable Author Statement
more info
PubMed 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
integral component of synaptic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
melanosome IEA
Inferred from Electronic Annotation
more info
 
secretory granule IEA
Inferred from Electronic Annotation
more info
 
synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
synaptophysin-like protein 1
Names
pantophysin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006754.4NP_006745.1  synaptophysin-like protein 1 isoform a

    See identical proteins and their annotated locations for NP_006745.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC005095, BC061887, BE048753, DA780897, S72481
    Consensus CDS
    CCDS5736.1
    UniProtKB/Swiss-Prot
    Q16563
    UniProtKB/TrEMBL
    A4D0R1
    Related
    ENSP00000011473.2, ENST00000011473.6
    Conserved Domains (1) summary
    pfam01284
    Location:104231
    MARVEL; Membrane-associating domain
  2. NM_182715.3NP_874384.1  synaptophysin-like protein 1 isoform b

    See identical proteins and their annotated locations for NP_874384.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AC005095, BC016835, BE048753, CB989012
    Consensus CDS
    CCDS47685.1
    UniProtKB/Swiss-Prot
    Q16563
    Related
    ENSP00000388336.2, ENST00000455385.6
    Conserved Domains (1) summary
    pfam01284
    Location:86213
    MARVEL; Membrane-associating domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    106090362..106112576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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