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Smim14 small integral membrane protein 14 [ Mus musculus (house mouse) ]

Gene ID: 68552, updated on 26-Sep-2022

Summary

Official Symbol
Smim14provided by MGI
Official Full Name
small integral membrane protein 14provided by MGI
Primary source
MGI:MGI:1915802
See related
Ensembl:ENSMUSG00000037822 AllianceGenome:MGI:1915802
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MAd4; 1110003E01Rik; 1700127H04Rik; 5430439C17Rik
Summary
Acts upstream of or within blastocyst hatching. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including bone; central nervous system; definitive endoderm; early conceptus; and secondary oocyte. Orthologous to human SMIM14 (small integral membrane protein 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 25.8), genital fat pad adult (RPKM 20.0) and 28 other tissues See more
Orthologs
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Genomic context

See Smim14 in Genome Data Viewer
Location:
5; 5 C3.1
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (65604187..65694492, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (65446844..65537149, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm1569 Neighboring gene lipoic acid synthetase Neighboring gene UDP-glucose dehydrogenase Neighboring gene predicted gene, 40309 Neighboring gene ubiquitin-conjugating enzyme E2K Neighboring gene PDS5 cohesin associated factor A Neighboring gene predicted gene, 24399

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Clone Names

  • MGC7185

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within blastocyst hatching IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small integral membrane protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001376971.1NP_001363900.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  2. NM_001376972.1NP_001363901.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  3. NM_001376973.1NP_001363902.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Related
    ENSMUSP00000113456.2, ENSMUST00000121661.8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  4. NM_001376974.1NP_001363903.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  5. NM_001376975.1NP_001363904.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  6. NM_001376976.1NP_001363905.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  7. NM_001376977.1NP_001363906.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  8. NM_001376978.1NP_001363907.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  9. NM_001376979.1NP_001363908.1  small integral membrane protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136513
    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)
  10. NM_133697.4NP_598458.1  small integral membrane protein 14

    See identical proteins and their annotated locations for NP_598458.1

    Status: VALIDATED

    Source sequence(s)
    AC136513, AK164394, CJ052807
    Consensus CDS
    CCDS19309.1
    UniProtKB/Swiss-Prot
    Q91VT8
    Related
    ENSMUSP00000122363.2, ENSMUST00000139122.8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    65604187..65694492 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165458.1XP_036021351.1  small integral membrane protein 14 isoform X1

    UniProtKB/Swiss-Prot
    Q91VT8
    Conserved Domains (1) summary
    pfam11027
    Location:397
    DUF2615; Protein of unknown function (DUF2615)