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Ddo D-aspartate oxidase [ Rattus norvegicus (Norway rat) ]

Gene ID: 685325, updated on 18-Apr-2019

Summary

Official Symbol
Ddoprovided by RGD
Official Full Name
D-aspartate oxidaseprovided by RGD
Primary source
RGD:1595123
See related
Ensembl:ENSRNOG00000000582
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Kidney (RPKM 83.9), Muscle (RPKM 37.4) and 7 other tissues See more

Genomic context

See Ddo in Genome Data Viewer
Location:
20q13
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (48739812..48758958, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 20 NC_005119.3 (50384344..50403396, complement)

Chromosome 20 - NC_005119.4Genomic Context describing neighboring genes Neighboring gene cell division cycle 40 Neighboring gene methyltransferase like 24 Neighboring gene hypothetical protein LOC688623 Neighboring gene glutaminyl-tRNA amidotransferase subunit QRSL1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Homology

  • Homologs of the Ddo gene: The Ddo gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, C.elegans, K.lactis, S.pombe, M.oryzae, N.crassa, and frog.
  • Orthologs

Gene Ontology Provided by RGD

Function Evidence Code Pubs
D-amino-acid oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
D-aspartate oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
D-aspartate oxidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
FAD binding IEA
Inferred from Electronic Annotation
more info
 
cofactor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 
signaling receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
D-amino acid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
D-amino acid catabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
aspartate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
aspartate catabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
aspartate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
aspartate metabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
grooming behavior IEA
Inferred from Electronic Annotation
more info
 
grooming behavior ISO
Inferred from Sequence Orthology
more info
PubMed 
hormone metabolic process IEA
Inferred from Electronic Annotation
more info
 
hormone metabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
insemination IEA
Inferred from Electronic Annotation
more info
 
insemination ISO
Inferred from Sequence Orthology
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
D-aspartate oxidase
NP_001102935.1
XP_017457261.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109465.2NP_001102935.1  D-aspartate oxidase

    See identical proteins and their annotated locations for NP_001102935.1

    Status: VALIDATED

    Source sequence(s)
    AABR07045478
    UniProtKB/TrEMBL
    D3ZDM7
    Related
    ENSRNOP00000000710.3, ENSRNOT00000000710.5
    Conserved Domains (2) summary
    pfam01266
    Location:5324
    DAO; FAD dependent oxidoreductase
    cl21724
    Location:188256
    GAG_Lyase; Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005119.4 Reference Rnor_6.0 Primary Assembly

    Range
    48739812..48758958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017601772.1XP_017457261.1  D-aspartate oxidase isoform X1

Alternate Rn_Celera

Genomic

  1. AC_000088.1 Alternate Rn_Celera

    Range
    44899117..44918244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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