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Ly6g6c lymphocyte antigen 6 family member G6C [ Mus musculus (house mouse) ]

Gene ID: 68468, updated on 5-Mar-2024

Summary

Official Symbol
Ly6g6cprovided by MGI
Official Full Name
lymphocyte antigen 6 family member G6Cprovided by MGI
Primary source
MGI:MGI:2148930
See related
Ensembl:ENSMUSG00000092586 AllianceGenome:MGI:2148930
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G6c; NG24; 1110003M04Rik
Summary
Enables identical protein binding activity. Acts upstream of or within response to bacterium. Part of protein-containing complex. Colocalizes with external side of plasma membrane. Is expressed in several structures, including brain; liver; lung; metanephros; and spleen. Orthologous to human LY6G6C (lymphocyte antigen 6 family member G6C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 153.4), testis adult (RPKM 51.0) and 1 other tissue See more
Orthologs
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Genomic context

See Ly6g6c in Genome Data Viewer
Location:
17 B1; 17 18.59 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (35286301..35289024)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35067325..35070048)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11641 Neighboring gene DDAH family member 2, ADMA independent Neighboring gene megakaryocyte and platelet inhibitory receptor G6b Neighboring gene G6b opposite strand Neighboring gene lymphocyte antigen 6 family member G6D Neighboring gene STARR-seq mESC enhancer starr_42446 Neighboring gene lymphocyte antigen 6 family member G6E Neighboring gene lymphocyte antigen 6 family member G6F

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information

Markers

Clone Names

  • MGC144235, MGC144236

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within response to bacterium IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
colocalizes_with external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of protein-containing complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lymphocyte antigen 6 complex locus protein G6c
Names
lymphocyte antigen 6 complex G6C
lymphocyte antigen 6 complex, locus G6C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023463.3NP_075952.1  lymphocyte antigen 6 complex locus protein G6c precursor

    See identical proteins and their annotated locations for NP_075952.1

    Status: VALIDATED

    Source sequence(s)
    AA061950, AK003375
    Consensus CDS
    CCDS28677.1
    UniProtKB/Swiss-Prot
    Q9Z1Q4
    UniProtKB/TrEMBL
    G3UYS0, Q545T2
    Related
    ENSMUSP00000133510.2, ENSMUST00000173478.2
    Conserved Domains (1) summary
    cl10471
    Location:22103
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    35286301..35289024
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)