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Fbxl15 F-box and leucine-rich repeat protein 15 [ Mus musculus (house mouse) ]

Gene ID: 68431, updated on 12-Aug-2019

Summary

Official Symbol
Fbxl15provided by MGI
Official Full Name
F-box and leucine-rich repeat protein 15provided by MGI
Primary source
MGI:MGI:1915681
See related
Ensembl:ENSMUSG00000025226
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fbxo37; 0710008C12Rik
Expression
Ubiquitous expression in duodenum adult (RPKM 21.3), adrenal adult (RPKM 18.4) and 28 other tissues See more
Orthologs

Genomic context

See Fbxl15 in Genome Data Viewer
Location:
19; 19 C3
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (46328184..46330446)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (46402674..46404936)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4833438C02 gene Neighboring gene nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 Neighboring gene pleckstrin and Sec7 domain containing Neighboring gene CUE domain containing 2 Neighboring gene predicted gene, 36493 Neighboring gene microRNA 146b Neighboring gene RIKEN cDNA 2310034G01 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G2/M transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
bone mineralization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of BMP signaling pathway ISO
Inferred from Sequence Orthology
more info
 
protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SCF ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
F-box/LRR-repeat protein 15
Names
F-box only protein 37

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133694.2NP_598455.2  F-box/LRR-repeat protein 15

    See identical proteins and their annotated locations for NP_598455.2

    Status: VALIDATED

    Source sequence(s)
    AI594908, AW124512, AW825726, CK791452
    Consensus CDS
    CCDS38007.1
    UniProtKB/Swiss-Prot
    Q91W61
    Related
    ENSMUSP00000026256.2, ENSMUST00000026256.8
    Conserved Domains (3) summary
    cd09293
    Location:139268
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:6288
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam00646
    Location:1855
    F-box; F-box domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p6 C57BL/6J

    Range
    46328184..46330446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527316.4XP_006527379.1  F-box/LRR-repeat protein 15 isoform X1

    Conserved Domains (3) summary
    cd09293
    Location:175304
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:125151
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam00646
    Location:1855
    F-box; F-box domain
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