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Mturn maturin, neural progenitor differentiation regulator homolog (Xenopus) [ Mus musculus (house mouse) ]

Gene ID: 68235, updated on 30-Apr-2024

Summary

Official Symbol
Mturnprovided by MGI
Official Full Name
maturin, neural progenitor differentiation regulator homolog (Xenopus)provided by MGI
Primary source
MGI:MGI:1915485
See related
Ensembl:ENSMUSG00000038065 AllianceGenome:MGI:1915485
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410066E13Rik; B230212L03Rik
Summary
Involved in positive regulation of megakaryocyte differentiation. Predicted to be located in cytoplasm. Is expressed in several structures, including central nervous system; ileum; male reproductive gland or organ; notochord; and retina. Orthologous to human MTURN (maturin, neural progenitor differentiation regulator homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 30.4), CNS E14 (RPKM 17.3) and 19 other tissues See more
Orthologs
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Genomic context

See Mturn in Genome Data Viewer
Location:
6 B3; 6 27.07 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (54658609..54680840)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (54681624..54703855)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene FK506 binding protein 14 Neighboring gene pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 Neighboring gene STARR-seq mESC enhancer starr_15954 Neighboring gene predicted gene, 34249 Neighboring gene STARR-seq mESC enhancer starr_15956 Neighboring gene STARR-seq mESC enhancer starr_15957 Neighboring gene predicted gene, 44008 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:54760023-54760206 Neighboring gene STARR-positive B cell enhancer ABC_E10381 Neighboring gene zinc and ring finger 2 Neighboring gene STARR-seq mESC enhancer starr_15969 Neighboring gene nucleotide-binding oligomerization domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
maturin
Names
UPF0452 protein C7orf41 homolog
maturin neural progenitor differentiation regulator protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289740.1NP_001276669.1  maturin isoform a

    See identical proteins and their annotated locations for NP_001276669.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (a).
    Source sequence(s)
    AC084800, BC052467, BY266709
    Consensus CDS
    CCDS20158.2
    UniProtKB/Swiss-Prot
    Q8CGA4
    Related
    ENSMUSP00000140586.2, ENSMUST00000190641.7
    Conserved Domains (1) summary
    pfam15167
    Location:4131
    DUF4581; Domain of unknown function (DUF4581)
  2. NM_001289741.1NP_001276670.1  maturin isoform b

    See identical proteins and their annotated locations for NP_001276670.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains alternate 3' exon structure, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is longer than isoform a.
    Source sequence(s)
    AC084800, BC052467, BY266709
    Consensus CDS
    CCDS80537.1
    UniProtKB/TrEMBL
    A0A087WQV4
    Related
    ENSMUSP00000140358.2, ENSMUST00000187701.2
    Conserved Domains (1) summary
    pfam15167
    Location:4129
    DUF4581; Domain of unknown function (DUF4581)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    54658609..54680840
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241447.3XP_011239749.1  maturin isoform X1

    See identical proteins and their annotated locations for XP_011239749.1

    UniProtKB/TrEMBL
    A0A087WQV4
    Conserved Domains (1) summary
    pfam15167
    Location:4129
    DUF4581; Domain of unknown function (DUF4581)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_026629.3: Suppressed sequence

    Description
    NM_026629.3: This RefSeq was permanently suppressed because currently there is insufficient support for the protein.