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Cntd1 cyclin N-terminal domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 68107, updated on 8-May-2024

Summary

Official Symbol
Cntd1provided by MGI
Official Full Name
cyclin N-terminal domain containing 1provided by MGI
Primary source
MGI:MGI:1923965
See related
Ensembl:ENSMUSG00000078653 AllianceGenome:MGI:1923965
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cntd; 1700051C09Rik; 4921513J16Rik; 5430417M23Rik
Summary
Acts upstream of or within reciprocal meiotic recombination and spermatogenesis. Predicted to be active in site of double-strand break. Orthologous to human CNTD1 (cyclin N-terminal domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 20.6), bladder adult (RPKM 6.3) and 18 other tissues See more
Orthologs
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Genomic context

See Cntd1 in Genome Data Viewer
Location:
11 D; 11 64.56 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101170029..101179527)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101279203..101288701)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene WNK lysine deficient protein kinase 4 Neighboring gene cytochrome C oxidase assembly factor 3 Neighboring gene beclin 1, autophagy related Neighboring gene STARR-positive B cell enhancer ABC_E2370 Neighboring gene STARR-positive B cell enhancer ABC_E7066 Neighboring gene proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) Neighboring gene amine oxidase copper containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC11788

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of meiotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
is_active_in site of double-strand break IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cyclin N-terminal domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026562.2NP_080838.1  cyclin N-terminal domain-containing protein 1

    See identical proteins and their annotated locations for NP_080838.1

    Status: PROVISIONAL

    Source sequence(s)
    AK007245
    Consensus CDS
    CCDS25461.1
    UniProtKB/Swiss-Prot
    Q9D995, Q9D9L8
    Related
    ENSMUSP00000099396.5, ENSMUST00000103107.5
    Conserved Domains (1) summary
    cl00050
    Location:57180
    CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    101170029..101179527
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)