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Rprm reprimo, TP53 dependent G2 arrest mediator homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 680110, updated on 17-Aug-2024

Summary

Official Symbol
Rprmprovided by RGD
Official Full Name
reprimo, TP53 dependent G2 arrest mediator homologprovided by RGD
Primary source
RGD:1595512
See related
EnsemblRapid:ENSRNOG00000005109 AllianceGenome:RGD:1595512
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. Orthologous to human RPRM (reprimo, TP53 dependent G2 arrest mediator homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Uterus (RPKM 76.2), Brain (RPKM 26.1) and 4 other tissues See more
Orthologs
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Genomic context

See Rprm in Genome Data Viewer
Location:
3q12
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (58948618..58950035, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (38539581..38540998, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (39595301..39596718, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA40 Neighboring gene uncharacterized LOC108350373 Neighboring gene U6 spliceosomal RNA Neighboring gene dyskerin pseudouridine synthase 1, pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC109515

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein reprimo
Names
candidate mediator of the p53-dependent G2 arrest
reprimo, TP53 dependent G2 arrest mediator candidate

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044276.1NP_001037741.1  protein reprimo

    See identical proteins and their annotated locations for NP_001037741.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091400
    UniProtKB/Swiss-Prot
    Q5BJN9
    UniProtKB/TrEMBL
    A6JF35
    Related
    ENSRNOP00000006784.1, ENSRNOT00000006784.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    58948618..58950035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)