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Mrps11 mitochondrial ribosomal protein S11 [ Mus musculus (house mouse) ]

Gene ID: 67994, updated on 8-Dec-2022

Summary

Official Symbol
Mrps11provided by MGI
Official Full Name
mitochondrial ribosomal protein S11provided by MGI
Primary source
MGI:MGI:1915244
See related
Ensembl:ENSMUSG00000030611 AllianceGenome:MGI:1915244
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S11mt; MRP-S11; 0710005I03Rik
Summary
Predicted to enable mRNA 5'-UTR binding activity and small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mitochondrial translation; and ribosomal small subunit assembly. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPS11 (mitochondrial ribosomal protein S11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 23.6), liver E14.5 (RPKM 18.9) and 28 other tissues See more
Orthologs
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Genomic context

See Mrps11 in Genome Data Viewer
Location:
7; 7 D2
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (78432879..78442736)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (78783131..78792988)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30892 Neighboring gene mitochondrial ribosomal protein L46 Neighboring gene de-etiolated homolog 1 (Arabidopsis) Neighboring gene uncharacterized LOC118567516 Neighboring gene microRNA 7-2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA 5'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables small ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
PubMed 
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of mitochondrial small ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
28S ribosomal protein S11, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360702.1NP_001347631.1  28S ribosomal protein S11, mitochondrial isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC156556, AK160207
    Conserved Domains (1) summary
    cl00332
    Location:8116
    Ribosomal_S11; Ribosomal protein S11
  2. NM_026498.2NP_080774.2  28S ribosomal protein S11, mitochondrial isoform 1

    See identical proteins and their annotated locations for NP_080774.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK152027, BB840699
    Consensus CDS
    CCDS21374.1
    UniProtKB/TrEMBL
    Q3U8Y1
    Related
    ENSMUSP00000032840.5, ENSMUST00000032840.5
    Conserved Domains (1) summary
    cl00332
    Location:82190
    Ribosomal_S11; Ribosomal protein S11

RNA

  1. NR_153793.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice junction compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC156556

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    78432879..78442736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)