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Gipc1 GIPC PDZ domain containing family, member 1 [ Mus musculus (house mouse) ]

Gene ID: 67903, updated on 6-Nov-2018

Summary

Official Symbol
Gipc1provided by MGI
Official Full Name
GIPC PDZ domain containing family, member 1provided by MGI
Primary source
MGI:MGI:1926252
See related
Ensembl:ENSMUSG00000019433 Vega:OTTMUSG00000061609
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GIPC; TIP-2; TaxIP2; Semcap1; Glut1CIP; Rgs19ip1
Expression
Ubiquitous expression in stomach adult (RPKM 41.0), colon adult (RPKM 40.6) and 28 other tissues See more
Orthologs

Genomic context

See Gipc1 in Genome Data Viewer
Location:
8; 8 C2
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (83652678..83664789)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (86176577..86188688)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 42029 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene DnaJ heat shock protein family (Hsp40) member B1 Neighboring gene prostaglandin E receptor 1 (subtype EP1) Neighboring gene protein kinase N1 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 Neighboring gene adhesion G protein-coupled receptor E5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTPase activator activity TAS
Traceable Author Statement
more info
PubMed 
PDZ domain binding ISO
Inferred from Sequence Orthology
more info
 
actin binding IPI
Inferred from Physical Interaction
more info
PubMed 
myosin binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Schaffer collateral - CA1 synapse IDA
Inferred from Direct Assay
more info
PubMed 
Schaffer collateral - CA1 synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
brush border ISO
Inferred from Sequence Orthology
more info
 
cell cortex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
dendritic shaft IDA
Inferred from Direct Assay
more info
PubMed 
dendritic spine IDA
Inferred from Direct Assay
more info
PubMed 
endocytic vesicle ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
postsynapse IDA
Inferred from Direct Assay
more info
PubMed 
presynapse IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
PDZ domain-containing protein GIPC1
Names
GAIP C-terminus-interacting protein
RGS-GAIP interacting protein GIPC
RGS-GAIP-interacting protein
RGS19-interacting protein 1
SEMCAP-1
Tax interacting protein, clone 2
neurophilin1-IP
regulator of G-protein signaling 19 interacting protein 1
semaF cytoplasmic domain associated protein
semaF cytoplasmic domain-associated protein 1
synectin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018771.3NP_061241.1  PDZ domain-containing protein GIPC1

    See identical proteins and their annotated locations for NP_061241.1

    Status: PROVISIONAL

    Source sequence(s)
    BC003490
    Consensus CDS
    CCDS22457.1
    UniProtKB/Swiss-Prot
    Q9Z0G0
    Related
    ENSMUSP00000019577.8, OTTMUSP00000077934, ENSMUST00000019577.9, OTTMUST00000150312
    Conserved Domains (1) summary
    cd00992
    Location:132210
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

    Range
    83652678..83664789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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