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Mtln mitoregulin [ Mus musculus (house mouse) ]

Gene ID: 67885, updated on 12-May-2024


Official Symbol
Mtlnprovided by MGI
Official Full Name
mitoregulinprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000051319 AllianceGenome:MGI:1915135
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mpm; Moxi; 1500011K16Rik
Involved in several processes, including positive regulation of fatty acid beta-oxidation; positive regulation of sequestering of calcium ion; and striated muscle cell differentiation. Located in mitochondrial inner membrane. Is integral component of mitochondrial inner membrane. Is expressed in Meckel's cartilage; axial skeleton; esophagus; and retina nuclear layer. Orthologous to human MTLN (mitoregulin). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in subcutaneous fat pad adult (RPKM 40.0), ovary adult (RPKM 36.9) and 28 other tissues See more
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Genomic context

See Mtln in Genome Data Viewer
2 F1; 2 62.1 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (127633302..127634408, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (127791382..127792488, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_05629 Neighboring gene mal, T cell differentiation protein-like Neighboring gene STARR-seq mESC enhancer starr_05630 Neighboring gene nephronophthisis 1 (juvenile) homolog (human) Neighboring gene STARR-positive B cell enhancer ABC_E415 Neighboring gene STARR-seq mESC enhancer starr_05631 Neighboring gene BUB1, mitotic checkpoint serine/threonine kinase Neighboring gene acyl-Coenzyme A oxidase-like Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:127753660-127754051 Neighboring gene STARR-positive B cell enhancer ABC_E7858 Neighboring gene STARR-positive B cell enhancer ABC_E9204 Neighboring gene STARR-positive B cell enhancer ABC_E10140 Neighboring gene STARR-seq mESC enhancer starr_05633 Neighboring gene STARR-positive B cell enhancer ABC_E10141 Neighboring gene STARR-positive B cell enhancer ABC_E4497 Neighboring gene predicted gene, 23101

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
located_in mitochondrion IDA
Inferred from Direct Assay
more info
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
lncRNA-encoded micropeptide
micropeptide in mitochondria
micropeptide regulator of beta-oxidation
small integral membrane protein 37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384135.1NP_001371064.1  mitoregulin

    Status: VALIDATED

    Source sequence(s)
    ENSMUSP00000141107.2, ENSMUST00000135091.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000068.8 Reference GRCm39 C57BL/6J

    127633302..127634408 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_175125.2: Suppressed sequence

    NM_175125.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate, and because there is no support for the predicted protein.