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Cdca5 cell division cycle associated 5 [ Mus musculus (house mouse) ]

Gene ID: 67849, updated on 5-Mar-2024

Summary

Official Symbol
Cdca5provided by MGI
Official Full Name
cell division cycle associated 5provided by MGI
Primary source
MGI:MGI:1915099
See related
Ensembl:ENSMUSG00000024791 AllianceGenome:MGI:1915099
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610036L13Rik
Summary
Involved in mitotic sister chromatid cohesion. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human CDCA5 (cell division cycle associated 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E14 (RPKM 15.9), liver E14.5 (RPKM 14.6) and 16 other tissues See more
Orthologs
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Genomic context

Location:
19 A; 19 4.34 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6135127..6141803)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6085097..6091773)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene VPS51 GARP complex subunit Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:6077181-6077364 Neighboring gene transmembrane protein 262 Neighboring gene STARR-positive B cell enhancer ABC_E3238 Neighboring gene STARR-positive B cell enhancer ABC_E4262 Neighboring gene zinc finger like protein 1 Neighboring gene predicted gene 550 Neighboring gene N-acetylated alpha-linked acidic dipeptidase-like 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in double-strand break repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in double-strand break repair ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
involved_in mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic chromosome condensation ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic metaphase chromosome alignment IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitotic metaphase chromosome alignment ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic sister chromatid cohesion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitotic sister chromatid cohesion IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in mitotic sister chromatid cohesion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of exit from mitosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of exit from mitosis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of chromatin IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
sororin
Names
cell division cycle-associated protein 5
sororin p35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026410.3NP_080686.1  sororin

    See identical proteins and their annotated locations for NP_080686.1

    Status: PROVISIONAL

    Source sequence(s)
    AC131692
    Consensus CDS
    CCDS29493.1
    UniProtKB/Swiss-Prot
    Q78HI6, Q9CPY3
    Related
    ENSMUSP00000025704.3, ENSMUST00000025704.3
    Conserved Domains (1) summary
    pfam09666
    Location:88223
    Sororin; Sororin protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    6135127..6141803
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)