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Rab32 RAB32, member RAS oncogene family [ Mus musculus (house mouse) ]

Gene ID: 67844, updated on 13-Dec-2022

Summary

Official Symbol
Rab32provided by MGI
Official Full Name
RAB32, member RAS oncogene familyprovided by MGI
Primary source
MGI:MGI:1915094
See related
Ensembl:ENSMUSG00000019832 AllianceGenome:MGI:1915094
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810011A17Rik
Summary
Predicted to enable several functions, including AP-1 adaptor complex binding activity; AP-3 adaptor complex binding activity; and BLOC-2 complex binding activity. Predicted to be involved in several processes, including endosome to melanosome transport; melanosome assembly; and phagosome maturation. Located in melanosome. Is expressed in duodenum; ileum; metanephros; prostate gland; and testis. Orthologous to human RAB32 (RAB32, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in subcutaneous fat pad adult (RPKM 13.2), liver adult (RPKM 10.4) and 22 other tissues See more
Orthologs
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Genomic context

See Rab32 in Genome Data Viewer
Location:
10; 10 A1
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (10420783..10433951, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (10545039..10558207, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930598N05 gene Neighboring gene eukaryotic translation initiation factor 4A1 pseudogene Neighboring gene androglobin Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 23601

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables AP-1 adaptor complex binding ISO
Inferred from Sequence Orthology
more info
 
enables AP-3 adaptor complex binding ISO
Inferred from Sequence Orthology
more info
 
enables BLOC-2 complex binding ISO
Inferred from Sequence Orthology
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTP-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in antigen processing and presentation ISO
Inferred from Sequence Orthology
more info
 
involved_in endosome to melanosome transport ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in melanosome assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in melanosome organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitochondrion organization ISO
Inferred from Sequence Orthology
more info
 
involved_in phagosome maturation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in early endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
is_active_in melanosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in melanosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in melanosome ISO
Inferred from Sequence Orthology
more info
 
located_in melanosome membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondria-associated endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in phagocytic vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in vesicle IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026405.3NP_080681.1  ras-related protein Rab-32

    See identical proteins and their annotated locations for NP_080681.1

    Status: PROVISIONAL

    Source sequence(s)
    AK088661
    Consensus CDS
    CCDS23695.1
    UniProtKB/Swiss-Prot
    Q91YN4, Q9CZE3
    UniProtKB/TrEMBL
    Q0PD23
    Related
    ENSMUSP00000019974.4, ENSMUST00000019974.5
    Conserved Domains (2) summary
    smart00175
    Location:24193
    RAB; Rab subfamily of small GTPases
    cd04107
    Location:24222
    Rab32_Rab38; Rab GTPase families 18 (Rab18) and 32 (Rab32)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    10420783..10433951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)