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Idh3a isocitrate dehydrogenase 3 (NAD+) alpha [ Mus musculus (house mouse) ]

Gene ID: 67834, updated on 19-Apr-2019

Summary

Official Symbol
Idh3aprovided by MGI
Official Full Name
isocitrate dehydrogenase 3 (NAD+) alphaprovided by MGI
Primary source
MGI:MGI:1915084
See related
Ensembl:ENSMUSG00000032279
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AA407078; AI316514; 1110003P10Rik; 1500012E04Rik
Expression
Ubiquitous expression in heart adult (RPKM 153.2), cerebellum adult (RPKM 51.8) and 25 other tissues See more
Orthologs

Genomic context

See Idh3a in Genome Data Viewer
Location:
9; 9 A5.3
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (54586511..54604662)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (54434318..54452469)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 7 Neighboring gene calcium and integrin binding family member 2 Neighboring gene acyl-CoA synthetase bubblegum family member 1 Neighboring gene predicted gene, 39341

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NAD binding IEA
Inferred from Electronic Annotation
more info
 
isocitrate dehydrogenase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
isocitrate dehydrogenase (NAD+) activity ISO
Inferred from Sequence Orthology
more info
 
magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
2-oxoglutarate metabolic process ISO
Inferred from Sequence Orthology
more info
 
NADH metabolic process ISO
Inferred from Sequence Orthology
more info
 
isocitrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
isocitrate metabolic process ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tricarboxylic acid cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
mitochondrion HDA PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
myelin sheath HDA PubMed 

General protein information

Preferred Names
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
Names
NAD(+)-specific ICDH subunit alpha
isocitric dehydrogenase subunit alpha
NP_083849.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029573.2NP_083849.1  isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor

    See identical proteins and their annotated locations for NP_083849.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049956
    Consensus CDS
    CCDS23191.1
    UniProtKB/Swiss-Prot
    Q9D6R2
    Related
    ENSMUSP00000127526.1, ENSMUST00000167866.1
    Conserved Domains (1) summary
    TIGR00175
    Location:29362
    mito_nad_idh; isocitrate dehydrogenase, NAD-dependent, mitochondrial type

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    54586511..54604662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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