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Snrnp48 small nuclear ribonucleoprotein 48 (U11/U12) [ Mus musculus (house mouse) ]

Gene ID: 67797, updated on 5-Mar-2024

Summary

Official Symbol
Snrnp48provided by MGI
Official Full Name
small nuclear ribonucleoprotein 48 (U11/U12)provided by MGI
Primary source
MGI:MGI:1915047
See related
Ensembl:ENSMUSG00000021431 AllianceGenome:MGI:1915047
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C6orf151; 1110050F08Rik; 6530403A03Rik
Summary
Predicted to enable metal ion binding activity. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human SNRNP48 (small nuclear ribonucleoprotein U11/U12 subunit 48). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 11.5), limb E14.5 (RPKM 8.0) and 28 other tissues See more
Orthologs
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Genomic context

See Snrnp48 in Genome Data Viewer
Location:
13 A3.3; 13 18.04 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (38388880..38411639)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (38204914..38227663)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene cancer antigen 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:38129215-38129324 Neighboring gene RIO kinase 1 Neighboring gene STARR-seq mESC enhancer starr_34240 Neighboring gene STARR-seq mESC enhancer starr_34241 Neighboring gene desmoplakin Neighboring gene STARR-positive B cell enhancer ABC_E3077 Neighboring gene predicted gene, 40921 Neighboring gene predicted gene, 47978

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
U11/U12 small nuclear ribonucleoprotein 48 kDa protein
Names
U11/U12 snRNP 48 kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026382.2NP_080658.2  U11/U12 small nuclear ribonucleoprotein 48 kDa protein

    See identical proteins and their annotated locations for NP_080658.2

    Status: VALIDATED

    Source sequence(s)
    AK004216, AK012916, BY263553, BY430458
    Consensus CDS
    CCDS36635.1
    UniProtKB/Swiss-Prot
    Q8BIU0, Q8BJ30, Q8CFF6, Q8VDQ5, Q9CSG3, Q9CVM5, Q9D361
    Related
    ENSMUSP00000089230.6, ENSMUST00000091641.13
    Conserved Domains (1) summary
    pfam05253
    Location:5679
    zf-U11-48K; U11-48K-like CHHC zinc finger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    38388880..38411639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244332.3XP_011242634.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X3

    Conserved Domains (1) summary
    pfam05253
    Location:5679
    zf-U11-48K; U11-48K-like CHHC zinc finger
  2. XM_006516735.1XP_006516798.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X2

  3. XM_017315577.1XP_017171066.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X1