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Plgrkt plasminogen receptor, C-terminal lysine transmembrane protein [ Mus musculus (house mouse) ]

Gene ID: 67759, updated on 4-Dec-2022

Summary

Official Symbol
Plgrktprovided by MGI
Official Full Name
plasminogen receptor, C-terminal lysine transmembrane proteinprovided by MGI
Primary source
MGI:MGI:1915009
See related
Ensembl:ENSMUSG00000016495 AllianceGenome:MGI:1915009
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Plg-RKT; Plg-R(KT); 1110007H22Rik; 5033414D02Rik
Summary
Acts upstream of or within positive regulation of plasminogen activation. Is integral component of plasma membrane. Is expressed in thymus primordium. Orthologous to human PLGRKT (plasminogen receptor with a C-terminal lysine). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 21.8), thymus adult (RPKM 10.8) and 27 other tissues See more
Orthologs
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Genomic context

See Plgrkt in Genome Data Viewer
Location:
19; 19 C1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (29326004..29339340, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (29348599..29367292, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene insulin-like 6 Neighboring gene predicted gene, 52390 Neighboring gene relaxin 1 Neighboring gene CD274 antigen Neighboring gene predicted gene, 36043 Neighboring gene programmed cell death 1 ligand 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within chemotaxis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of plasminogen activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within positive regulation of plasminogen activation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
plasminogen receptor (KT)
Names
transmembrane protein C9orf46 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026362.2NP_080638.1  plasminogen receptor (KT)

    See identical proteins and their annotated locations for NP_080638.1

    Status: VALIDATED

    Source sequence(s)
    AK017215
    Consensus CDS
    CCDS29734.1
    UniProtKB/Swiss-Prot
    Q3TCJ3, Q9D3P8
    Related
    ENSMUSP00000120466.2, ENSMUST00000143467.8
    Conserved Domains (1) summary
    pfam10166
    Location:1134
    DUF2368; Uncharacterized conserved protein (DUF2368)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    29326004..29339340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251060.2XP_030106920.1  plasminogen receptor (KT) isoform X1

    UniProtKB/Swiss-Prot
    Q3TCJ3
    Conserved Domains (1) summary
    pfam10166
    Location:1134
    DUF2368; Uncharacterized conserved protein (DUF2368)
  2. XM_030251059.2XP_030106919.1  plasminogen receptor (KT) isoform X1

    UniProtKB/Swiss-Prot
    Q3TCJ3
    Related
    ENSMUSP00000016639.6, ENSMUST00000016639.12
    Conserved Domains (1) summary
    pfam10166
    Location:1134
    DUF2368; Uncharacterized conserved protein (DUF2368)
  3. XM_030251058.2XP_030106918.1  plasminogen receptor (KT) isoform X1

    UniProtKB/Swiss-Prot
    Q3TCJ3
    Conserved Domains (1) summary
    pfam10166
    Location:1134
    DUF2368; Uncharacterized conserved protein (DUF2368)