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Rpp21 ribonuclease P 21 subunit [ Mus musculus (house mouse) ]

Gene ID: 67676, updated on 11-Apr-2024


Official Symbol
Rpp21provided by MGI
Official Full Name
ribonuclease P 21 subunitprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000024446 AllianceGenome:MGI:1914926
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleus. Predicted to be part of nucleolar ribonuclease P complex. Orthologous to human RPP21 (ribonuclease P/MRP subunit p21). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in duodenum adult (RPKM 19.9), stomach adult (RPKM 18.6) and 28 other tissues See more
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Genomic context

See Rpp21 in Genome Data Viewer
17 B1; 17 19.01 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36566565..36568738, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (36255673..36257846, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene 4252 Neighboring gene non-histone chromosomal protein HMG-14 pseudogene Neighboring gene tripartite motif-containing 39 Neighboring gene histocompatibility 2, M region locus 10.2

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
enables ribonuclease P RNA binding ISO
Inferred from Sequence Orthology
more info
contributes_to ribonuclease P activity ISO
Inferred from Sequence Orthology
more info
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
involved_in tRNA 5'-leader removal ISO
Inferred from Sequence Orthology
more info
involved_in tRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
part_of multimeric ribonuclease P complex ISO
Inferred from Sequence Orthology
more info
part_of nucleolar ribonuclease P complex IBA
Inferred from Biological aspect of Ancestor
more info
located_in nucleus IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
ribonuclease P protein subunit p21
RNaseP protein p21
ribonuclease P 21kDa subunit
ribonucleoprotein V

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026308.2NP_080584.1  ribonuclease P protein subunit p21

    See identical proteins and their annotated locations for NP_080584.1


    Source sequence(s)
    Consensus CDS
    Q80XY3, Q811B7, Q8R040, Q9CPX1
    ENSMUSP00000025319.7, ENSMUST00000025319.7
    Conserved Domains (1) summary
    Rpr2; RNAse P Rpr2/Rpp21/SNM1 subunit domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000083.7 Reference GRCm39 C57BL/6J

    36566565..36568738 complement
    GenBank, FASTA, Sequence Viewer (Graphics)