U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slc25a30 solute carrier family 25, member 30 [ Mus musculus (house mouse) ]

Gene ID: 67554, updated on 8-Dec-2022

Summary

Go to the top of the page Help
Official Symbol
Slc25a30provided by MGI
Official Full Name
solute carrier family 25, member 30provided by MGI
Primary source
MGI:MGI:1914804
See related
Ensembl:ENSMUSG00000022003 AllianceGenome:MGI:1914804
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
KMCP1; 4933433D23Rik
Summary
Predicted to enable C4-dicarboxylate transmembrane transporter activity; antiporter activity; and sulfur compound transmembrane transporter activity. Predicted to be involved in anion transport. Located in mitochondrion. Is expressed in adrenal medulla; ganglia; medulla oblongata basal plate mantle layer; and metanephros. Orthologous to human SLC25A30 (solute carrier family 25 member 30). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 6.9), ovary adult (RPKM 6.5) and 25 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Slc25a30 in Genome Data Viewer
Location:
14; 14 D3
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (75994986..76024477, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (75757534..75787037, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene glutamate rich 6B Neighboring gene predicted gene, 23622 Neighboring gene component of oligomeric golgi complex 3 Neighboring gene predicted gene, 36271 Neighboring gene predicted gene 4285

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A new renal mitochondrial carrier, KMCP1, is up-regulated during tubular cell regeneration and induction of antioxidant enzymes. Haguenauer A, et al. J Biol Chem, 2005 Jun 10. PMID 15809292
  2. The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase. Groh BS, et al. EMBO Rep, 2016 May. PMID 27113764, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. KMCP1 is involved in situations in which mitochondrial metabolism is increased, in particular when the cellular redox balance tends toward a pro-oxidant status
    Title: A new renal mitochondrial carrier, KMCP1, is up-regulated during tubular cell regeneration and induction of antioxidant enzymes.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
kidney mitochondrial carrier protein 1
Names
VH186.2-D-J-C mu

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026232.3 → NP_080508.1  kidney mitochondrial carrier protein 1

    See identical proteins and their annotated locations for NP_080508.1

    Status: PROVISIONAL

    Source sequence(s)
    AC122285
    Consensus CDS
    CCDS27281.1
    UniProtKB/Swiss-Prot
    Q3UAD0, Q9CR58
    Related
    ENSMUSP00000022580.7, ENSMUST00000022580.8
    Conserved Domains (2) summary
    PTZ00169
    Location:9 → 289
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:199 → 289
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    75994986..76024477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519456.5 → XP_006519519.1  kidney mitochondrial carrier protein 1 isoform X2

    Conserved Domains (1) summary
    pfam00153
    Location:105 → 191
    Mito_carr; Mitochondrial carrier protein

  2. XM_006519455.5 → XP_006519518.1  kidney mitochondrial carrier protein 1 isoform X1

    Conserved Domains (1) summary
    pfam00153
    Location:105 → 191
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CR58.1 GenPept UniProtKB/Swiss-Prot:Q9CR58

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous