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Mtfr1 mitochondrial fission regulator 1 [ Mus musculus (house mouse) ]

Gene ID: 67472, updated on 26-Sep-2022

Summary

Official Symbol
Mtfr1provided by MGI
Official Full Name
mitochondrial fission regulator 1provided by MGI
Primary source
MGI:MGI:1914722
See related
Ensembl:ENSMUSG00000027601 AllianceGenome:MGI:1914722
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Chppr; Fam54a2; 1300002C08Rik; 1700080D04Rik; 2810026O10Rik; 4930579E05Rik
Summary
Involved in aerobic respiration. Located in mitochondrion. Is expressed in brain; embryo; and testis. Orthologous to human MTFR1 (mitochondrial fission regulator 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 71.8), liver E14 (RPKM 19.6) and 20 other tissues See more
Orthologs
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Genomic context

See Mtfr1 in Genome Data Viewer
Location:
3; 3 A2
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (19241481..19274981)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (19187315..19220817)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30341 Neighboring gene armadillo repeat containing 1 Neighboring gene phosphodiesterase 7A Neighboring gene testis-specific gene A8 protein-like Neighboring gene predicted gene, 52602

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitochondrial fission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial fission regulator 1
Names
chondrocyte protein with a poly-proline region

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001253390.2NP_001240319.1  mitochondrial fission regulator 1

    See identical proteins and their annotated locations for NP_001240319.1

    Status: VALIDATED

    Source sequence(s)
    AC127283, AK004846, AK006952, AK161251, BY429681
    Consensus CDS
    CCDS17256.1
    UniProtKB/Swiss-Prot
    Q99MB2, Q9CQZ4
    UniProtKB/TrEMBL
    Q3TTQ5
    Related
    ENSMUSP00000112752.2, ENSMUST00000119865.8
    Conserved Domains (1) summary
    pfam05308
    Location:24249
    Mito_fiss_reg; Mitochondrial fission regulator
  2. NM_001253391.2NP_001240320.1  mitochondrial fission regulator 1

    See identical proteins and their annotated locations for NP_001240320.1

    Status: VALIDATED

    Source sequence(s)
    AC127283, AK004846, AK006952, BY429681
    Consensus CDS
    CCDS17256.1
    UniProtKB/Swiss-Prot
    Q99MB2, Q9CQZ4
    UniProtKB/TrEMBL
    Q3TTQ5
    Related
    ENSMUSP00000112824.2, ENSMUST00000117529.8
    Conserved Domains (1) summary
    pfam05308
    Location:24249
    Mito_fiss_reg; Mitochondrial fission regulator
  3. NM_001356295.1NP_001343224.1  mitochondrial fission regulator 1

    Status: VALIDATED

    Source sequence(s)
    AC127283, BY429681
    Consensus CDS
    CCDS17256.1
    UniProtKB/Swiss-Prot
    Q9CQZ4
    UniProtKB/TrEMBL
    Q3TTQ5
    Conserved Domains (1) summary
    pfam05308
    Location:24249
    Mito_fiss_reg; Mitochondrial fission regulator
  4. NM_026182.6NP_080458.1  mitochondrial fission regulator 1

    See identical proteins and their annotated locations for NP_080458.1

    Status: VALIDATED

    Source sequence(s)
    AC127283, AK004846, BY143181, BY429681
    Consensus CDS
    CCDS17256.1
    UniProtKB/Swiss-Prot
    Q99MB2, Q9CQZ4
    UniProtKB/TrEMBL
    Q3TTQ5
    Related
    ENSMUSP00000119724.2, ENSMUST00000130645.8
    Conserved Domains (1) summary
    pfam05308
    Location:24249
    Mito_fiss_reg; Mitochondrial fission regulator

RNA

  1. NR_045575.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC127283, AK004846, BY143181, BY429681, CK625955

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    19241481..19274981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011249708.4XP_011248010.1  mitochondrial fission regulator 1 isoform X1

    See identical proteins and their annotated locations for XP_011248010.1

    UniProtKB/Swiss-Prot
    Q99MB2, Q9CQZ4
    UniProtKB/TrEMBL
    Q3TTQ5
    Conserved Domains (1) summary
    pfam05308
    Location:24249
    Mito_fiss_reg; Mitochondrial fission regulator
  2. XM_036163244.1XP_036019137.1  mitochondrial fission regulator 1 isoform X2

    Conserved Domains (1) summary
    pfam05308
    Location:24249
    Mito_fiss_reg; Mitochondrial fission regulator