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C1qtnf4 C1q and tumor necrosis factor related protein 4 [ Mus musculus (house mouse) ]

Gene ID: 67445, updated on 8-Feb-2024

Summary

Official Symbol
C1qtnf4provided by MGI
Official Full Name
C1q and tumor necrosis factor related protein 4provided by MGI
Primary source
MGI:MGI:1914695
See related
Ensembl:ENSMUSG00000040794 AllianceGenome:MGI:1914695
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Adin; CTRP4; 0710001E10Rik; 9430004J15Rik
Summary
Predicted to enable cytokine activity. Predicted to be involved in positive regulation of cytokine production and positive regulation of signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain and retina. Orthologous to human C1QTNF4 (C1q and TNF related 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 119.2), frontal lobe adult (RPKM 74.2) and 7 other tissues See more
Orthologs
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Genomic context

See C1qtnf4 in Genome Data Viewer
Location:
2 E1; 2 50.43 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (90713132..90720870)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (90882788..90890526)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene ATP/GTP binding protein-like 2 Neighboring gene STARR-seq mESC enhancer starr_05097 Neighboring gene predicted gene 13772 Neighboring gene STARR-seq mESC enhancer starr_05098 Neighboring gene STARR-positive B cell enhancer ABC_E11147 Neighboring gene mitochondrial carrier 2 Neighboring gene STARR-positive B cell enhancer ABC_E9517 Neighboring gene predicted gene, 32514 Neighboring gene NADH:ubiquinone oxidoreductase core subunit S3 Neighboring gene predicted gene, 54113

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (4)  1 citation

General protein information

Preferred Names
complement C1q tumor necrosis factor-related protein 4
Names
C1q/TNF-related protein 4
adiponectin n

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026161.3NP_080437.2  complement C1q tumor necrosis factor-related protein 4 precursor

    See identical proteins and their annotated locations for NP_080437.2

    Status: VALIDATED

    Source sequence(s)
    AK029777, BF458176, CX243534, DQ002397
    Consensus CDS
    CCDS16417.2
    UniProtKB/Swiss-Prot
    A2AFW1, Q4ZJN5, Q8R066, Q9D0W2, Q9DCB6
    UniProtKB/TrEMBL
    A0A3B0IP17
    Related
    ENSMUSP00000107091.3, ENSMUST00000111466.3
    Conserved Domains (1) summary
    pfam00386
    Location:30155
    C1q; C1q domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    90713132..90720870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251995.1XP_030107855.1  complement C1q tumor necrosis factor-related protein 4 isoform X1

    UniProtKB/Swiss-Prot
    A2AFW1, Q4ZJN5, Q8R066, Q9D0W2, Q9DCB6
    UniProtKB/TrEMBL
    A0A3B0IP17
    Conserved Domains (1) summary
    pfam00386
    Location:30155
    C1q; C1q domain
  2. XM_006500080.4XP_006500143.1  complement C1q tumor necrosis factor-related protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006500143.1

    UniProtKB/Swiss-Prot
    A2AFW1, Q4ZJN5, Q8R066, Q9D0W2, Q9DCB6
    UniProtKB/TrEMBL
    A0A3B0IP17
    Conserved Domains (1) summary
    pfam00386
    Location:30155
    C1q; C1q domain
  3. XM_006500079.2XP_006500142.1  complement C1q tumor necrosis factor-related protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006500142.1

    UniProtKB/Swiss-Prot
    A2AFW1, Q4ZJN5, Q8R066, Q9D0W2, Q9DCB6
    UniProtKB/TrEMBL
    A0A3B0IP17
    Conserved Domains (1) summary
    pfam00386
    Location:30155
    C1q; C1q domain
  4. XM_030251994.2XP_030107854.1  complement C1q tumor necrosis factor-related protein 4 isoform X1

    UniProtKB/Swiss-Prot
    A2AFW1, Q4ZJN5, Q8R066, Q9D0W2, Q9DCB6
    UniProtKB/TrEMBL
    A0A3B0IP17
    Conserved Domains (1) summary
    pfam00386
    Location:30155
    C1q; C1q domain