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Ccdc127 coiled-coil domain containing 127 [ Mus musculus (house mouse) ]

Gene ID: 67433, updated on 12-May-2024

Summary

Official Symbol
Ccdc127provided by MGI
Official Full Name
coiled-coil domain containing 127provided by MGI
Primary source
MGI:MGI:1914683
See related
Ensembl:ENSMUSG00000021578 AllianceGenome:MGI:1914683
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A430066A18; C130002N06; 0610011N22Rik; 5430420E17Rik
Summary
Orthologous to human CCDC127 (coiled-coil domain containing 127). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 14.1), cerebellum adult (RPKM 4.7) and 22 other tissues See more
Orthologs
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Genomic context

See Ccdc127 in Genome Data Viewer
Location:
13 C1; 13 40.17 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (74498436..74513902)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (74350317..74365783)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene programmed cell death 6 Neighboring gene succinate dehydrogenase complex, subunit A, flavoprotein (Fp) Neighboring gene STARR-positive B cell enhancer ABC_E10800 Neighboring gene leucine rich repeat containing 14B Neighboring gene zinc finger protein 72 Neighboring gene STARR-seq mESC enhancer starr_35006 Neighboring gene BCL2-like 13 (apoptosis facilitator) pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7251 Neighboring gene STARR-seq mESC enhancer starr_35008 Neighboring gene ferritin light polypeptide 1, pseudogene 1 Neighboring gene microRNA 692-3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 127

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168658.1NP_001162129.1  coiled-coil domain-containing protein 127 isoform 2

    See identical proteins and their annotated locations for NP_001162129.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding region, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AK164539, CT009486
    Consensus CDS
    CCDS49314.1
    UniProtKB/TrEMBL
    E0CYP1
    Related
    ENSMUSP00000124193.2, ENSMUST00000160021.8
  2. NM_001168659.1NP_001162130.1  coiled-coil domain-containing protein 127 isoform 1

    See identical proteins and their annotated locations for NP_001162130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AK002564, AK164539, CT009486
    Consensus CDS
    CCDS26644.1
    UniProtKB/Swiss-Prot
    Q3TC33, Q3TPA8, Q9CQ15
    UniProtKB/TrEMBL
    E0CYX9
    Related
    ENSMUSP00000022063.8, ENSMUST00000022063.14
    Conserved Domains (1) summary
    pfam17380
    Location:47137
    DUF5401; Family of unknown function (DUF5401)
  3. NM_024201.3NP_077163.1  coiled-coil domain-containing protein 127 isoform 1

    See identical proteins and their annotated locations for NP_077163.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AK164539, BC049099, CT009486
    Consensus CDS
    CCDS26644.1
    UniProtKB/Swiss-Prot
    Q3TC33, Q3TPA8, Q9CQ15
    UniProtKB/TrEMBL
    E0CYX9
    Related
    ENSMUSP00000123805.2, ENSMUST00000162376.2
    Conserved Domains (1) summary
    pfam17380
    Location:47137
    DUF5401; Family of unknown function (DUF5401)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    74498436..74513902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)