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Gpx7 glutathione peroxidase 7 [ Mus musculus (house mouse) ]

Gene ID: 67305, updated on 8-Feb-2024

Summary

Official Symbol
Gpx7provided by MGI
Official Full Name
glutathione peroxidase 7provided by MGI
Primary source
MGI:MGI:1914555
See related
Ensembl:ENSMUSG00000028597 AllianceGenome:MGI:1914555
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GPX6; 3110050F08Rik
Summary
Predicted to enable catalase activity. Predicted to be involved in response to oxidative stress. Predicted to be located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; integumental system; nose; and skeleton. Orthologous to human GPX7 (glutathione peroxidase 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 39.9), limb E14.5 (RPKM 29.2) and 21 other tissues See more
Orthologs
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Genomic context

See Gpx7 in Genome Data Viewer
Location:
4 C7; 4 50.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108257414..108263910, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108400217..108406713, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46889 Neighboring gene VISTA enhancer mm1490 Neighboring gene predicted gene, 54250 Neighboring gene shisa like 2A Neighboring gene STARR-seq mESC enhancer starr_11044 Neighboring gene predicted gene, 32297 Neighboring gene STARR-seq mESC enhancer starr_11045 Neighboring gene predicted gene, 40223 Neighboring gene STARR-positive B cell enhancer ABC_E3501 Neighboring gene ribosomal protein L9 pseudogene Neighboring gene predicted gene, 24967 Neighboring gene terminal uridylyl transferase 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables catalase activity ISO
Inferred from Sequence Orthology
more info
 
enables glutathione peroxidase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables peroxidase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glutathione peroxidase 7
Names
GPx-7
GSHPx-7
NP_077160.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024198.3NP_077160.1  glutathione peroxidase 7 precursor

    See identical proteins and their annotated locations for NP_077160.1

    Status: PROVISIONAL

    Source sequence(s)
    AK165221
    Consensus CDS
    CCDS18450.1
    UniProtKB/Swiss-Prot
    Q99LJ6
    UniProtKB/TrEMBL
    Q3TNK3
    Related
    ENSMUSP00000030332.7, ENSMUST00000030332.7
    Conserved Domains (2) summary
    TIGR02540
    Location:23175
    gpx7; putative glutathione peroxidase Gpx7
    pfam00578
    Location:26155
    AhpC-TSA; AhpC/TSA family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    108257414..108263910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)