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LOC6730443 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II [ Drosophila simulans ]

Gene ID: 6730443, updated on 15-Sep-2023

Summary

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Gene symbol
LOC6730443
Gene description
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
Locus tag
Dsimw501_GD23017
See related
EnsemblRapid:LOC6730443
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila simulans
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
GD23017; GD23017-PA; GD23017-PB; GD23017-PC; GD23017-PD; GD23017-PE; GD23017-PF
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Genomic context

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Location:
chromosome: 2L
Exon count:
18
Annotation release Status Assembly Chr Location
103 current Prin_Dsim_3.1 (GCF_016746395.2) 2L NC_052520.2 (371466..411892)
102 previous assembly Prin_Dsim_3.0 (GCF_016746395.1) 2L NC_052520.1 (371464..412324)

Chromosome 2L - NC_052520.2Genomic Context describing neighboring genes Neighboring gene stress-induced-phosphoprotein 1 Neighboring gene phosphatidylinositol 3-kinase regulatory subunit gamma Neighboring gene lectizyme Neighboring gene lectizyme Neighboring gene trypsin Neighboring gene uncharacterized LOC27206533 Neighboring gene mediator of RNA polymerase II transcription subunit 1.1 Neighboring gene equilibrative nucleoside transporter 1 Neighboring gene homeobox protein aristaless

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
Names
Dsim\GD23017
Dsim\GD23017-PA
Dsim\GD23017-PB
Dsim\GD23017-PC
Dsim\GD23017-PD
Dsim\GD23017-PE
Dsim\GD23017-PF
dsim_GLEANR_6758

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Drosophila simulans Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Prin_Dsim_3.1

Genomic

  1. NC_052520.2 Reference Prin_Dsim_3.1

    Range
    371466..411892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016179320.3 → XP_016022907.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X1

    UniProtKB/TrEMBL
    B4Q625
    Related
    XP_016022907.1, XM_016179320.3
    Conserved Domains (5) summary
    cd00275
    Location:736 → 855
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:317 → 702
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02222
    Location:213 → 850
    PLN02222; phosphoinositide phospholipase C 2
    cd13361
    Location:20 → 145
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam09279
    Location:225 → 317
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

  2. XM_044923926.1 → XP_044779861.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X4

    UniProtKB/TrEMBL
    A0A0J9TCG8
    Related
    XP_044779861.1, XM_044923926.1
    Conserved Domains (5) summary
    PTZ00121
    Location:981 → 1246
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:736 → 855
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:317 → 702
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:20 → 145
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16213
    Location:151 → 305
    EFh_PI-PLC21; EF-hand motif found in phosphoinositide phospholipase PLC21 and similar proteins

  3. XM_044923924.1 → XP_044779859.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X2

    Related
    XP_044779859.1, XM_044923924.1
    Conserved Domains (5) summary
    PTZ00121
    Location:976 → 1248
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:736 → 855
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:317 → 702
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:20 → 145
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16213
    Location:151 → 305
    EFh_PI-PLC21; EF-hand motif found in phosphoinositide phospholipase PLC21 and similar proteins

  4. XM_044923927.1 → XP_044779862.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X5

    Related
    XP_044779862.1, XM_044923927.1
    Conserved Domains (5) summary
    PTZ00121
    Location:976 → 1241
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:736 → 855
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:317 → 702
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:20 → 145
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16213
    Location:151 → 305
    EFh_PI-PLC21; EF-hand motif found in phosphoinositide phospholipase PLC21 and similar proteins

  5. XM_044923925.1 → XP_044779860.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X3

    UniProtKB/TrEMBL
    A0A0J9QTB1
    Related
    XP_044779860.1, XM_044923925.1
    Conserved Domains (5) summary
    PTZ00121
    Location:975 → 1247
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:736 → 855
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:317 → 702
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:20 → 145
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16213
    Location:151 → 305
    EFh_PI-PLC21; EF-hand motif found in phosphoinositide phospholipase PLC21 and similar proteins

  6. XM_044923928.1 → XP_044779863.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X6

    UniProtKB/TrEMBL
    A0A0J9QU17
    Related
    XP_044779863.1, XM_044923928.1
    Conserved Domains (5) summary
    PTZ00121
    Location:975 → 1240
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:736 → 855
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:317 → 702
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:20 → 145
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16213
    Location:151 → 305
    EFh_PI-PLC21; EF-hand motif found in phosphoinositide phospholipase PLC21 and similar proteins

  7. XM_016179319.3 → XP_016022906.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X1

    UniProtKB/TrEMBL
    B4Q625
    Related
    XP_016022906.1, XM_016179319.3
    Conserved Domains (5) summary
    cd00275
    Location:736 → 855
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:317 → 702
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02222
    Location:213 → 850
    PLN02222; phosphoinositide phospholipase C 2
    cd13361
    Location:20 → 145
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam09279
    Location:225 → 317
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
Nucleotide Protein Strain
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