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Tmem19 transmembrane protein 19 [ Mus musculus (house mouse) ]

Gene ID: 67226, updated on 19-Apr-2024

Summary

Official Symbol
Tmem19provided by MGI
Official Full Name
transmembrane protein 19provided by MGI
Primary source
MGI:MGI:1914476
See related
Ensembl:ENSMUSG00000069520 AllianceGenome:MGI:1914476
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810428F02Rik
Summary
Predicted to be integral component of membrane. Predicted to be active in membrane. Orthologous to human TMEM19 (transmembrane protein 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 21.5), liver adult (RPKM 10.8) and 28 other tissues See more
Orthologs
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Genomic context

Location:
10 D2; 10 63.51 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (115176644..115198406, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (115340739..115362522, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3916 Neighboring gene STARR-positive B cell enhancer ABC_E6923 Neighboring gene predicted gene 10752 Neighboring gene predicted gene, 53632 Neighboring gene STARR-seq mESC enhancer starr_27937 Neighboring gene STARR-seq mESC enhancer starr_27939 Neighboring gene STARR-seq mESC enhancer starr_27942 Neighboring gene soc-2 (suppressor of clear) homolog pseudogene Neighboring gene THAP domain containing, apoptosis associated protein 2 Neighboring gene predicted gene, 53633 Neighboring gene STARR-positive B cell enhancer ABC_E1128 Neighboring gene zinc finger, C3H1-type containing

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359470.1NP_001346399.1  transmembrane protein 19 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC153497, AK034298, AK138931, BB636118
    Consensus CDS
    CCDS88087.1
    UniProtKB/TrEMBL
    A0A1W2P7P6
    Related
    ENSMUSP00000151334.2, ENSMUST00000217887.2
    Conserved Domains (1) summary
    pfam01940
    Location:74337
    DUF92; Integral membrane protein DUF92
  2. NM_001359471.1NP_001346400.1  transmembrane protein 19 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153497, AK018383, AK034298, AK138931
    Consensus CDS
    CCDS24178.1
    UniProtKB/Swiss-Prot
    Q3UU09, Q8BY23, Q8BZK7, Q91W52
    UniProtKB/TrEMBL
    A0A1W2P7P6
    Conserved Domains (1) summary
    pfam01940
    Location:59322
    DUF92; Integral membrane protein DUF92
  3. NM_001359472.1NP_001346401.1  transmembrane protein 19 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153497, AK034298, AK138931, CX200523
    Consensus CDS
    CCDS24178.1
    UniProtKB/Swiss-Prot
    Q3UU09, Q8BY23, Q8BZK7, Q91W52
    UniProtKB/TrEMBL
    A0A1W2P7P6
    Related
    ENSMUSP00000151753.2, ENSMUST00000217884.2
    Conserved Domains (1) summary
    pfam01940
    Location:59322
    DUF92; Integral membrane protein DUF92
  4. NM_133683.4NP_598444.1  transmembrane protein 19 isoform 2

    See identical proteins and their annotated locations for NP_598444.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variants 3 and 4, encodes isoform 2.
    Source sequence(s)
    AC153497, AK034298, AK138931
    Consensus CDS
    CCDS24178.1
    UniProtKB/Swiss-Prot
    Q3UU09, Q8BY23, Q8BZK7, Q91W52
    UniProtKB/TrEMBL
    A0A1W2P7P6
    Related
    ENSMUSP00000089808.6, ENSMUST00000092170.7
    Conserved Domains (1) summary
    pfam01940
    Location:59322
    DUF92; Integral membrane protein DUF92

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    115176644..115198406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513978.3XP_006514041.1  transmembrane protein 19 isoform X2

    See identical proteins and their annotated locations for XP_006514041.1

    UniProtKB/TrEMBL
    A0A1W2P7R5
    Related
    ENSMUSP00000151762.2, ENSMUST00000218731.2
    Conserved Domains (1) summary
    pfam01940
    Location:1222
    DUF92; Integral membrane protein DUF92
  2. XM_006513977.2XP_006514040.1  transmembrane protein 19 isoform X2

    See identical proteins and their annotated locations for XP_006514040.1

    UniProtKB/TrEMBL
    A0A1W2P7R5
    Conserved Domains (1) summary
    pfam01940
    Location:1222
    DUF92; Integral membrane protein DUF92
  3. XM_036155960.1XP_036011853.1  transmembrane protein 19 isoform X1

    UniProtKB/TrEMBL
    A0A1W2P7P6
    Conserved Domains (1) summary
    pfam01940
    Location:23263
    DUF92; Integral membrane protein DUF92