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Med29 mediator complex subunit 29 [ Mus musculus (house mouse) ]

Gene ID: 67224, updated on 5-Mar-2024

Summary

Official Symbol
Med29provided by MGI
Official Full Name
mediator complex subunit 29provided by MGI
Primary source
MGI:MGI:1914474
See related
Ensembl:ENSMUSG00000003444 AllianceGenome:MGI:1914474
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ixl; 2810405O22Rik
Summary
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of mediator complex. Orthologous to human MED29 (mediator complex subunit 29). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 28.8), adrenal adult (RPKM 23.3) and 28 other tissues See more
Orthologs
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Genomic context

See Med29 in Genome Data Viewer
Location:
7 A3; 7 16.72 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28084667..28092126, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28385247..28392690, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 2 Neighboring gene STARR-positive B cell enhancer ABC_E1728 Neighboring gene STARR-seq mESC enhancer starr_18413 Neighboring gene nuclear encoded tRNA isoleucine 16 (anticodon TAT) Neighboring gene STARR-positive B cell enhancer ABC_E2821 Neighboring gene STARR-seq mESC enhancer starr_18414 Neighboring gene Paf1, RNA polymerase II complex component Neighboring gene zinc finger protein 36 Neighboring gene STARR-positive B cell enhancer ABC_E289 Neighboring gene sterile alpha motif domain containing 4B Neighboring gene STARR-positive B cell enhancer ABC_E240 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29225831-29226014 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29231461-29231644 Neighboring gene STARR-seq mESC enhancer starr_18417 Neighboring gene glia maturation factor, gamma

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of core mediator complex ISO
Inferred from Sequence Orthology
more info
 
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mediator complex ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mediator of RNA polymerase II transcription subunit 29
Names
intersex-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026042.4NP_080318.2  mediator of RNA polymerase II transcription subunit 29

    See identical proteins and their annotated locations for NP_080318.2

    Status: VALIDATED

    Source sequence(s)
    AC149606
    Consensus CDS
    CCDS21042.1
    UniProtKB/Swiss-Prot
    Q9DB91
    Related
    ENSMUSP00000003536.9, ENSMUST00000003536.9
    Conserved Domains (1) summary
    pfam11568
    Location:52186
    Med29; Mediator complex subunit 29

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    28084667..28092126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)