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L3hypdh L-3-hydroxyproline dehydratase (trans-) [ Mus musculus (house mouse) ]

Gene ID: 67217, updated on 10-Mar-2024

Summary

Official Symbol
L3hypdhprovided by MGI
Official Full Name
L-3-hydroxyproline dehydratase (trans-)provided by MGI
Primary source
MGI:MGI:1914467
See related
Ensembl:ENSMUSG00000019718 AllianceGenome:MGI:1914467
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810055F11Rik
Summary
Enables hydro-lyase activity. Orthologous to human L3HYPDH (trans-L-3-hydroxyproline dehydratase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in adrenal adult (RPKM 31.4), ovary adult (RPKM 18.1) and 18 other tissues See more
Orthologs
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Genomic context

See L3hypdh in Genome Data Viewer
Location:
12 C3; 12 30.2 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (72114745..72132206, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (72069518..72085433, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40440 Neighboring gene STARR-seq mESC enhancer starr_32432 Neighboring gene predicted gene 7986 Neighboring gene G protein-coupled receptor 135 Neighboring gene STARR-seq mESC enhancer starr_32433 Neighboring gene predicted gene 3225 Neighboring gene STARR-positive B cell enhancer ABC_E3055 Neighboring gene JNK1/MAPK8-associated membrane protein Neighboring gene predicted gene, 19135 Neighboring gene coiled-coil domain containing 175 Neighboring gene zinc finger protein 146 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydro-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables hydro-lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables hydro-lyase activity ISO
Inferred from Sequence Orthology
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
NOT enables proline racemase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables trans-L-3-hydroxyproline dehydratase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
trans-L-3-hydroxyproline dehydratase
Names
probable proline racemase
trans-3-hydroxy-l-proline dehydratase
NP_080314.1
XP_011242463.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026038.2NP_080314.1  trans-L-3-hydroxyproline dehydratase

    See identical proteins and their annotated locations for NP_080314.1

    Status: PROVISIONAL

    Source sequence(s)
    AK018449
    Consensus CDS
    CCDS25966.1
    UniProtKB/Swiss-Prot
    B8JJ82, Q99KB5, Q9CXA2
    Related
    ENSMUSP00000019862.3, ENSMUST00000019862.3
    Conserved Domains (2) summary
    PRK13970
    Location:20347
    PRK13970; hydroxyproline-2-epimerase; Provisional
    pfam05544
    Location:22352
    Pro_racemase; Proline racemase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    72114745..72132206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244161.4XP_011242463.1  trans-L-3-hydroxyproline dehydratase isoform X1

    Conserved Domains (1) summary
    pfam05544
    Location:22314
    Pro_racemase; Proline racemase